protamines - CISMeF

Preferred Label : protamines;

MeSH definition : A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692);

MeSH synonym : Protamine;

MeSH hyponym : protamine chloride; Protamine Sulfate; Sulfate, Protamine; Chloride, Protamine;

MeSH annotation : heparin antag;

Is substance : O;

Details

Origin ID

D011479;

UMLS CUI

C0033603;

ATC code(s)
- protamine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- PROTAMINE [SMS substance]
- Protamine [LOINC component]
- Protamine [ICD-11 Extension code]
- Protamine [NCIt concept]
- Protamine (substance) [SNOMED CT concept]
- protamine [ATC Code]
Pharmacological action(s)
- heparin antagonists [MeSH Descriptor]
Record concept(s)
- Protamine Sulfate [MeSH concept]
- protamine chloride [MeSH concept]
- protamines [MeSH concept]
Related MeSH Supplementary Concept(s)
- PRM1 protein, human [MeSH Supplementary Concept]
- Prm1 protein, mouse [MeSH Supplementary Concept]
- Prm1 protein, rat [MeSH Supplementary Concept]
- ProtA protein, Drosophila [MeSH Supplementary Concept]
- ProtB protein, Drosophila [MeSH Supplementary Concept]
- deoxyribonucleoprotamine [MeSH Supplementary Concept]
- ekmolin [MeSH Supplementary Concept]
- galline [MeSH Supplementary Concept]
- glucagon, protamine zinc- [MeSH Supplementary Concept]
- iridine [MeSH Supplementary Concept]
- mugiline beta [MeSH Supplementary Concept]
- neutral protamine lispro insulin [MeSH Supplementary Concept]
- protamine +18RGD [MeSH Supplementary Concept]
- protamine 1, lizard sperm [MeSH Supplementary Concept]
- protamine 2 [MeSH Supplementary Concept]
- protamine A, acipenser stellatus [MeSH Supplementary Concept]
- protamine B, acipenser gueldenstaedtii [MeSH Supplementary Concept]
- protamine P1 [MeSH Supplementary Concept]
- protamine P2 [MeSH Supplementary Concept]
- protamine P2 precursor [MeSH Supplementary Concept]
- protamine P3 [MeSH Supplementary Concept]
- protamine P4 [MeSH Supplementary Concept]
- protamine R3 [MeSH Supplementary Concept]
- protamine St1 [MeSH Supplementary Concept]
- protamine Z1 [MeSH Supplementary Concept]
- protamine Z2 [MeSH Supplementary Concept]
- protamine Z3 [MeSH Supplementary Concept]
- protamine heparin aggregate [MeSH Supplementary Concept]
- protamine zinc [MeSH Supplementary Concept]
- protamine-ferritin conjugate [MeSH Supplementary Concept]
- protamine-heparin membrane [MeSH Supplementary Concept]
- protamine-like protein III [MeSH Supplementary Concept]
- sagaxine 1 [MeSH Supplementary Concept]
- sagaxine 2 [MeSH Supplementary Concept]
- sardaine Z1 [MeSH Supplementary Concept]
- sardaine Z2 [MeSH Supplementary Concept]
- scombrine [MeSH Supplementary Concept]
- somatostatin, protamine zinc- [MeSH Supplementary Concept]
- stellin [MeSH Supplementary Concept]
- sturin [MeSH Supplementary Concept]
- thynnine [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing protamine (medicinal product) [SNOMED CT concept]
- Protamine [LOINC component]
- Protamine [NCIt concept]
- Protamine (substance) [SNOMED CT concept]
- protamine [ATC Code]
Validated automatic mappings to BTNT
- Protamine Sulfate [NCIt concept]
- Protamine sulfate [ICD-11 Extension code]
- Protamine sulfate [SMS substance]
- Protamine sulfate (substance) [SNOMED CT concept]
- protamine sulfate [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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