Protamine Sulfate

Preferred Label : Protamine Sulfate;

NCIt synonyms : Protamine Sulphate;

NCIt definition : The sulfate salt form of protamine, a highly basic protein rich in arginine and a heparin antagonist, that can be used to neutralize heparin-induced anticoagulation. Upon intravenous administration, the cationic hydrogenated protamine reacts with anionic heparin to form an inactive salt aggregate, which has no anticoagulant activity. Protamine, when administered alone in the absence of heparin, is a weak anticoagulant.;

UNII : 0DE9724IHC;

CAS number : 9009-65-8;

Chemical formula : H2O4S;

Codes from synonyms : 422;

Details

Origin ID

C84123;

UMLS CUI

C0033602;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- protamines [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Protamine [NCIt concept]
is_salt_form_of
- Protamine [NCIt concept]

Keyword's position in hierarchy(ies) :

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