propylthiouracil

Preferred Label : propylthiouracil;

MeSH definition : A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534);

MeSH synonym : 6 propyl 2 thiouracil; 6-propyl-2-thiouracil;

MeSH CAS label : 4(1H)-Pyrimidinone, 2,3-dihydro-6-propyl-2-thioxo-;

MeSH Related Number : 51-52-5 (Propylthiouracil);

Registry Number MeSH : 51-52-5;

MeSH annotation : a thyroid antag;

Wikipedia link : https://en.wikipedia.org/wiki/Propylthiouracil;

Codes EINECS : 200-103-2;

Is substance : O;

UNII : 721M9407IY;

InChIKey : KNAHARQHSZJURB-UHFFFAOYSA-N;

Details

Origin ID

D011441;

UMLS CUI

C0033511;

ATC code(s)
- propylthiouracil [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- propylthiouracil [Substance BNPC]
Currated CISMeF NLP mapping
- Propylthiouracil [ICD-11 Extension code]
- Propylthiouracil [ICHI extension code]
- Propylthiouracil [SMS substance]
- Propylthiouracil [NCIt concept]
- Propylthiouracil [LOINC component]
- Propylthiouracil (substance) [SNOMED CT concept]
Pharmacological action(s)
- antimetabolites [MeSH Descriptor]
- antithyroid agents [MeSH Descriptor]
Record concept(s)
- propylthiouracil [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-propyl-4-thiouracil [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing propylthiouracil (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing propylthiouracil (medicinal product) [SNOMED CT concept]
- Propylthiouracil [ICD-11 Extension code]
- Propylthiouracil [NCIt concept]
- Propylthiouracil [LOINC component]
- Propylthiouracil (substance) [SNOMED CT concept]
- propylthiouracil [ATC Code]
- propylthiouracil [Substance BNPC]
- propylthiouracil preparation [SNOMED Notion]
Validated automatic mappings to BTNT
- propylthiouracil [ATC Code]

Keyword's position in hierarchy(ies) :

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