thiouracil - CISMeF

Preferred Label : thiouracil;

MeSH definition : Occurs in seeds of Brassica and Crucifera species. Thiouracil has been used as antithyroid, coronary vasodilator, and in congestive heart failure although its use has been largely supplanted by other drugs. It is known to cause blood dyscrasias and suspected of terato- and carcinogenesis.;

CISMeF synonym : 2-thiouracil;

MeSH CAS label : 4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo-;

MeSH Related Number : 141-90-2 (Thiouracil);

Registry Number MeSH : 141-90-2;

MeSH annotation : a thyroid antag;

Codes EINECS : 205-508-8;

Is substance : O;

UNII : 59X161SCYL;

InChIKey : ZEMGGZBWXRYJHK-UHFFFAOYSA-N;

Details

Origin ID

D013889;

UMLS CUI

C0039957;

ATC code(s)
- thiouracils [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- 2-thiouracil [Substance BNPC]
- Thiouracil (benzyl) (methyl) (propyl) [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Thiouracil [SMS substance]
- Thiouracil [NCIt concept]
- Thiouracil (substance) [SNOMED CT concept]
- thiouracil [SNOMED Notion]
- thiouracils [ATC Code]
Pharmacological action(s)
- antithyroid agents [MeSH Descriptor]
- vasodilator agents [MeSH Descriptor]
Record concept(s)
- thiouracil [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1,3-dimethyl-4-thiouracil [MeSH Supplementary Concept]
- 1-benzyl-2-thio-5,6-dihydrouracil [MeSH Supplementary Concept]
- 2,4-dithiouracil [MeSH Supplementary Concept]
- 2-thio-4-hydrazinouracil [MeSH Supplementary Concept]
- 4,5-diamino-2-thiouracil [MeSH Supplementary Concept]
- 4-thiouracil [MeSH Supplementary Concept]
- 5-(2-thiazolylazo)thiouracil [MeSH Supplementary Concept]
- 5-bromo-2-thiouracil [MeSH Supplementary Concept]
- 5-carbethoxy-2-thiouracil [MeSH Supplementary Concept]
- 5-dihydroxyboryl-2-thiouracil [MeSH Supplementary Concept]
- 5-dimethylaminomethyl-2-thiouracil [MeSH Supplementary Concept]
- 5-ethyl-6-(1-naphthylmethyl)-2-thiouracil [MeSH Supplementary Concept]
- 5-isopropyl-1-((hydroxyethoxy)methyl)-6-(3,5-dimethylphenythio)-2-thiouracil [MeSH Supplementary Concept]
- 5-phenylthioacyclouridine [MeSH Supplementary Concept]
- 6-amino-2-thiouracil [MeSH Supplementary Concept]
- 6-anilino-2-thiouracil [MeSH Supplementary Concept]
- 6-methyl-2-thiouracil [MeSH Supplementary Concept]
- 6-phenylthiouracil [MeSH Supplementary Concept]
- 6-trifluoromethyl-2-thiouracil [MeSH Supplementary Concept]
- benzylthiouracil [MeSH Supplementary Concept]
- iodothiouracil [MeSH Supplementary Concept]
- metaltite [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 2-thiouracil [Substance BNPC]
- Thiouracil [NCIt concept]
- Thiouracil (benzyl) (methyl) (propyl) [ICD-11 Extension code]
- Thiouracil (substance) [SNOMED CT concept]
- thiouracil [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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