complement factor D

Preferred Label : complement factor D;

MeSH definition : A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE.;

MeSH synonym : convertase, c3pa; c3pase; convertase, proactivator; complement d component; c3 proactivator convertase; proactivator convertase; protein d, complement; gbgase; convertase activator, c3; factor d, complement; complement protein d; properdin factor d; factor d, properdin; convertase, c3 proactivator; adipsin; c3 convertase activator; activator, c3 convertase; d component of complement; 28 kda protein, adipocyte; c3pa convertase; factor d;

Registry Number MeSH : EC 3.4.21.46;

MeSH annotation : see SCR for organism-specific terms;

Wikipedia link : https://en.wikipedia.org/wiki/C3 proactivator convertase;

Is substance : O;

UNII : EC 3.4.21.46;

Details

Origin ID

D011416;

UMLS CUI

C0033457;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- C>2< complement assay (procedure) [SNOMED CT concept]
- C>5< complement assay (procedure) [SNOMED CT concept]
- CFD wt Allele [NCIt concept]
- Complement component (substance) [SNOMED CT concept]
- Complement factor [MedDRA Preferred Term]
- Complement factor (substance) [SNOMED CT concept]
- Complement factor D [OMIM gene]
- Complement factor b [OMIM Phenotype]
- Complement factor increased [MedDRA Preferred Term]
- Factor [NCIt concept]
- Leukemia Inhibitory Factor [NCIt concept]
- Mathematical Factor [NCIt concept]
- blood-coagulation factor ii [Substance BNPC]
- blood-coagulation factor iii [Substance BNPC]
- blood-coagulation factor v [Substance BNPC]
- blood-coagulation factor x [Substance BNPC]
- complement component, nos [SNOMED Notion]
- complement factor D [ORDO Gene]
- complement factor D [HGNC gene]
- complement factor b, nos [SNOMED Notion]
- complement factor bb [SNOMED Notion]
- f factor [SNOMED Notion]
- factor [IUPAC Term]
- factor h [SNOMED Notion]
- fibrinogens [Substance BNPC]
- obsolete complement factor D activity [GO term]
- r factor [SNOMED Notion]
Currated CISMeF NLP mapping
- Complement Factor D [NCIt concept]
- Complement factor D [LOINC component]
- Complement factor D (substance) [SNOMED CT concept]
- complement factor d [SNOMED Notion]
Indexing information
- BCX 1470 [MeSH Supplementary Concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- complement factor D [MeSH concept]
Related MeSH Supplementary Concept(s)
- CFD protein, human [MeSH Supplementary Concept]
- complement factor D deficiency [MeSH Supplementary Concept]
- complement factor D, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- Complement factor D [LOINC component]
- Complement factor D (substance) [SNOMED CT concept]
- complement factor d [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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