pentoxifylline

Preferred Label : pentoxifylline;

MeSH definition : A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.;

MeSH synonym : oxpentifylline;

MeSH hyponym : pentoxil; torental; agapurin; BL-191; trental; BL 191; BL191;

MeSH CAS label : 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-;

MeSH Related Number : 6493-05-6 (Pentoxifylline);

Registry Number MeSH : 6493-05-6;

Wikipedia link : https://en.wikipedia.org/wiki/Pentoxifylline;

Codes EINECS : 229-374-5;

Is substance : O;

UNII : SD6QCT3TSU;

InChIKey : BYPFEZZEUUWMEJ-UHFFFAOYSA-N;

Details

Origin ID

D010431;

UMLS CUI

C0030899;

ATC code(s)
- pentoxifylline [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 5-hydroxymethyl-6-methyluracil [Substance BNPC]
CISMeF manual mappings
- Oxpentifylline adverse reaction (disorder) [SNOMED CT concept]
- Pentoxifylline measurement (procedure) [SNOMED CT concept]
- pentoxifylline [Substance BNPC]
Currated CISMeF NLP mapping
- Pentoxifylline [ICD-11 Extension code]
- Pentoxifylline [ICHI extension code]
- Pentoxifylline [SMS substance]
- Pentoxifylline [NCIt concept]
- Pentoxifylline [LOINC component]
- Pentoxifylline (substance) [SNOMED CT concept]
- Pentoxyfylline [LOINC component]
- pentoxifylline [SNOMED Notion]
Pharmacological action(s)
- free radical scavengers [MeSH Descriptor]
- phosphodiesterase inhibitors [MeSH Descriptor]
- platelet aggregation inhibitors [MeSH Descriptor]
- radiation-protective agents [MeSH Descriptor]
- vasodilator agents [MeSH Descriptor]
Record concept(s)
- BL-191 [MeSH concept]
- agapurin [MeSH concept]
- pentoxifylline [MeSH concept]
- pentoxil [MeSH concept]
- torental [MeSH concept]
- trental [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-(3'-carboxypropyl)-3,7-dimethylxanthine [MeSH Supplementary Concept]
- 1-(4'-carboxybutyl)-3,7-dimethylxanthine [MeSH Supplementary Concept]
- 1-(5-hydroxy-5-methylhexyl)-3-methylxanthine [MeSH Supplementary Concept]
- 1-(5-hydroxyhexyl)-3,7-dimethylxanthine [MeSH Supplementary Concept]
- 8-oxolisofylline [MeSH Supplementary Concept]
- 8-oxopentoxifylline [MeSH Supplementary Concept]
- lisofylline [MeSH Supplementary Concept]
- lisofylline 4,5-diol [MeSH Supplementary Concept]
- pentoxifylline-alpha-methoxy-alpha-(trifluoromethyl)phenylacetate ester [MeSH Supplementary Concept]
- pentoxifylline-tocopherol-clodronate [MeSH Supplementary Concept]
- torbafylline [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pentoxifylline [LOINC component]
- Pentoxifylline [ICD-11 Extension code]
- Pentoxifylline [NCIt concept]
- Pentoxifylline (substance) [SNOMED CT concept]
- Pentoxyfylline [LOINC component]
- Product containing pentoxifylline (medicinal product) [SNOMED CT concept]
- pentoxifylline [ATC Code]
- pentoxifylline [Substance BNPC]
- pentoxifylline [SNOMED Notion]
Validated automatic mappings to BTNT
- pentoxifylline [ATC Code]

Keyword's position in hierarchy(ies) :

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