Preferred Label : penicillanic acid;

MeSH definition : A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed);

MeSH synonym : acid, penicillanic;

CISMeF synonym : (2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;

MeSH CAS label : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, (2S-cis)-;

Registry Number MeSH : 87-53-6;

MeSH annotation : do not confuse with PENICILLIC ACID;

Codes EINECS : 201-750-3;

Is substance : O;

Details


Main resources

You can consult :

A building block of penicillin, devoid of significant antibacterial activity. (From Merck Index, 11th ed)

https://ansm.sante.fr/informations-de-securite/Zerbaxa-R-ceftolozane-tazobactam-1-g-0-5-g-poudre-pour-solution-a-diluer-pour-perfusion-RAPPEL-DE-LOT-MONDIAL
2021
false
false
false
France
French
pharmacovigilance note
ceftolozane, tazobactam drug combination
drug contamination
ceftolozane
drug combinations
Safety-Based drug withdrawals
infusions, intravenous
Tazobactam
cephalosporins
penicillanic acid

---
https://ansm.sante.fr/actualites/lantibiotique-zerbaxa-ceftolozane-tazobactam-nest-plus-disponible-en-raison-dun-arret-temporaire-de-la-production
2020
false
false
false
France
French
pharmacovigilance note
drug contamination
anti-bacterial agents
ceftolozane, tazobactam drug combination
ceftolozane sulfate
Tazobactam Sodium
france
ceftolozane and beta-lactamase inhibitor
ceftolozane
Tazobactam
cephalosporins
penicillanic acid

---
https://www.has-sante.fr/jcms/p_3152698/fr/zerbaxa
2020
false
false
false
France
French
treatment outcome
insurance, health, reimbursement
ceftolozane, tazobactam drug combination
drug combinations
ceftolozane
anti-bacterial agents
Tazobactam
ceftolozane and beta-lactamase inhibitor
beta-Lactamase Inhibitors
evaluation of the transparency committee
pseudomonas aeruginosa
pseudomonas infections
Infection Pseudomonas aeruginosa
cephalosporins
penicillanic acid
penicillanic acid

---
Piperacillin/Tazobactam for Injection and Piperacillin for Injection
Product monograph updates
https://www.hc-sc.gc.ca/dhp-mps/medeff/bulletin/hpiw-ivps_2016-02-fra.php#a44
2016
false
false
false
Canada
French
English
pharmacovigilance note
journal article
piperacillin
drug combinations
piperacillin
piperacillin and beta-lactamase inhibitor
anti-bacterial agents
injections
antibiotic therapy
drug hypersensitivity syndrome
penicillanic acid
penicillanic acid
penicillanic acid
Piperacillin, Tazobactam Drug Combination
Tazobactam

---
http://www.has-sante.fr/portail/jcms/c_2658642/fr/zerbaxa
http://www.has-sante.fr/portail/jcms/c_2658642/fr/zerbaxa-ceftolozane/tazobactam-cephalosporine-et-inhibiteur-de-lactamase
2016
false
false
false
France
French
treatment outcome
ceftolozane, tazobactam drug combination
ceftolozane, tazobactam drug combination
ceftolozane
ceftolozane
anti-bacterial agents
anti-bacterial agents
pyelonephritis
intraabdominal infections
urinary tract infections
complicated intra-abdominal infections
INFECTION AGGRAVATED
infusions, intravenous
beta-Lactamase Inhibitors
beta-Lactamase Inhibitors
aged
drug combinations
ceftolozane and beta-lactamase inhibitor
antibiotic therapy
evaluation of the transparency committee
guidelines for drug use
pseudomonas infections
pseudomonas aeruginosa
Infection caused by extended spectrum beta-lactamase producing bacteria (disorder)
infection due to pseudomonas aeruginosa
cephalosporins
penicillanic acid
penicillanic acid
cephalosporins
penicillanic acid
Tazobactam
Tazobactam

---
Summary Basis of Decision (SBD) for Zerbaxa
Zerbaxa 1.5 g /vial, ceftolozane (1 g as ceftolozane sulfate) and tazobactam (0.5 g as tazobactam sodium), powder for solution, intravenous
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailTwo.php?linkID=SBD00247
2015
false
false
false
false
Canada
French
summary of product characteristics
ceftolozane, tazobactam drug combination
ceftolozane, tazobactam drug combination
ceftolozane
ceftolozane
drug combinations
drug approval
canada
ceftolozane sulfate
ceftolozane sulfate
anti-bacterial agents
anti-bacterial agents
beta-Lactamase Inhibitors
beta-Lactamase Inhibitors
intraabdominal infections
complicated intra-abdominal infections
Complicated infection
urinary tract infections
pyelonephritis
infusions, intravenous
treatment outcome
ceftolozane and beta-lactamase inhibitor
antibiotic therapy
cephalosporins
penicillanic acid
penicillanic acid
cephalosporins
penicillanic acid
Tazobactam
Tazobactam

---
https://www.ema.europa.eu/medicines/human/EPAR/Zerbaxa
2015
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
ceftolozane, tazobactam drug combination
ceftolozane, tazobactam drug combination
ceftolozane
ceftolozane
anti-bacterial agents
anti-bacterial agents
pyelonephritis
intraabdominal infections
urinary tract infections
complicated intra-abdominal infections
INFECTION AGGRAVATED
infusions, intravenous
beta-Lactamase Inhibitors
beta-Lactamase Inhibitors
drug monitoring
product surveillance, postmarketing
pregnancy
breast feeding
drug interactions
aged
drug compounding
drug evaluation, preclinical
risk management
drug combinations
ceftolozane and beta-lactamase inhibitor
antibiotic therapy
cephalosporins
penicillanic acid
penicillanic acid
cephalosporins
penicillanic acid
Tazobactam
Tazobactam

---
http://www.lecrat.eu/?s=Tazocilline
2013
France
French
antibiotic therapy
piperacillin
drug combinations
pregnancy
penicillanic acid
anti-bacterial agents
piperacillin and beta-lactamase inhibitor
drug information
Piperacillin, Tazobactam Drug Combination
Tazobactam

---
http://www.meddispar.fr/medicaments/3691921
2008
France
French
piperacillin
penicillanic acid
drug combinations
infusions, parenteral
drug prescriptions
legislation, drug
piperacillin and beta-lactamase inhibitor
drug information
Piperacillin, Tazobactam Drug Combination
Tazobactam

---
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26/04/2025


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