Preferred Label : beta 2-Microglobulin;
MeSH definition : An 11-kDa protein associated with the outer membrane of many cells including lymphocytes.
It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin
is generally required for the transport of class I heavy chains from the endoplasmic
reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in
serum, csf, and urine of normal people, and to a much greater degree in the urine
and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.; An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES.
It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin
is generally required for the transport of class I heavy chains from the endoplasmic
reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in
serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater
degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure,
or kidney transplants.;
MeSH synonym : thymotaxin; beta 2 microglobulin;
CISMeF synonym : 2-microglobulin, beta;
MeSH annotation : /biosyn /physiol /blood permitted;
Wikipedia link : https://en.wikipedia.org/wiki/Beta 2-microglobulin;
Is substance : O;
Origin ID : D001613;
UMLS CUI : C0005149;
Allowable qualifiers
- Indexing information
- Ne pas confondre avec
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- Related MeSH Supplementary Concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
An 11-kDa protein associated with the outer membrane of many cells including lymphocytes.
It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin
is generally required for the transport of class I heavy chains from the endoplasmic
reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in
serum, csf, and urine of normal people, and to a much greater degree in the urine
and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.
An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES.
It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin
is generally required for the transport of class I heavy chains from the endoplasmic
reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in
serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater
degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure,
or kidney transplants.
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=85446
false
true
false
France
scientific and technical information
joint diseases
beta 2-Microglobulin
amyloidosis, nos
dialysis
amyloidosis
amyloidosis
amylose
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