amitriptyline - CISMeF

Preferred Label : amitriptyline;

Obsolete resource : false;

MeSH definition : Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.;

CISMeF synonym : 549-18-8 (Amitriptyline hydrochloride); APS brand of amitriptyline hydrochloride; Rhône-Poulenc rorer brand of amitriptyline hydrochloride; rhône poulenc rorer brand of amitriptyline hydrochloride; amrad brand of amitriptyline hydrochloride; cahill may roberts brand of amitriptyline embonate; merck sharp & dohme brand of amitriptyline hydrochloride; DDSA brand of amitriptyline hydrochloride; merck sharp & dohme brand of amitriptyline embonate; zeneca brand of amitriptyline hydrochloride; cahill may roberts brand of amitriptyline hydrochloride; neuro hexal brand of amitriptyline hydrochloride; hexal brand of amitriptyline hydrochloride; protea brand of amitriptyline hydrochloride; beta, amitriptylin; betapharm brand of amitriptyline hydrochloride; desitin brand of amitriptyline hydrochloride; rodleben brand of amitriptyline hydrochloride; amitriptylinneuraxpharm; neuraxpharm brand of amitriptyline hydrochloride; roche brand of amitriptyline hydrochloride; alphapharm brand of amitriptyline hydrochloride; parke davis brand of amitriptyline hydrochloride; merck brand of amitriptyline hydrochloride; bayer brand of amitriptyline hydrochloride; lundbeck brand of amitriptyline hydrochloride; krewel brand of amitriptyline hydrochloride; goldshield brand of amitriptyline hydrochloride; douglas brand of amitriptyline hydrochloride; psicofarma brand of amitriptyline hydrochloride; ApoAmitriptyline; apotex brand of amitriptyline hydrochloride;

DeCS synonym : Endep;

MeSH hyponym : amitriptylin RPh; tryptine; amitrip; lentizol; amitriptylin desitin; domical; syneudon; Apo-Amitriptyline; saroten; amitrol; sarotex; anapsique; amineurin; triptafen; amitriptylin beta; laroxyl; amitriptyline hydrochloride; amitriptylin-neuraxpharm; damilen; novoprotect; tryptizol; Desitin, Amitriptylin; RPh, Amitriptylin; Amitriptylin Neuraxpharm; Apo Amitriptyline; Elavil; Tryptanol;

CISMeF hyponym : endep;

MeSH CAS label : 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-;

MeSH Related Number : amitriptyline hydrochloride; 17086-03-2 (pamoate (2:1)); 30227-34-0 (maleate (1:1)); 50-48-6 (Amitriptyline); 51052-95-0 (maleate (2:1)); 51390-24-0 (maleate); 549-18-8 (HCl); 87987-25-5 (phosphate (1:1)); 26LUD4JO9K;

Registry Number MeSH : 50-48-6;

Related CAS MeSH : 26LUD4JO9K (Amitriptyline hydrochloride);

Wikipedia link : https://en.wikipedia.org/wiki/Amitriptyline;

Codes EINECS : 200-041-6;

Is substance : O;

UNII : 1806D8D52K;

InChIKey : KRMDCWKBEZIMAB-UHFFFAOYSA-N;

Details

Origin ID

D000639;

UMLS CUI

C0002600;

ATC code(s)
- amitriptyline [ATC Code]
- amitriptyline and psycholeptics [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Aminotriazole (substance) [SNOMED CT concept]
- Amitriptyline Hydrochloride [NCIt concept]
- Amitriptyline hydrochloride [Substance BNPC]
- Amitriptyline hydrochloride (substance) [SNOMED CT concept]
- Amitrole [NCIt concept]
- Laroxyl [ICHI extension code]
- Saroten [ICHI extension code]
- Tryptizol [ICHI extension code]
- amitriptyline [EMDN type]
- amitriptyline [medical devices type]
- amitriptyline hydrochloride [SNOMED Notion]
- amitrole [Substance BNPC]
CISMeF manual mappings
- Amitriptyline adverse reaction (disorder) [SNOMED CT concept]
- Amitriptyline measurement (procedure) [SNOMED CT concept]
- Poisoning caused by amitriptyline (disorder) [SNOMED CT concept]
- amitriptyline [Substance BNPC]
Pharmacological action(s)
- adrenergic uptake inhibitors [MeSH Descriptor]
- analgesics, non-narcotic [MeSH Descriptor]
- antidepressive agents, tricyclic [MeSH Descriptor]
Record concept(s)
- Apo-Amitriptyline [MeSH concept]
- Endep [MeSH concept]
- amineurin [MeSH concept]
- amitrip [MeSH concept]
- amitriptylin RPh [MeSH concept]
- amitriptylin beta [MeSH concept]
- amitriptylin desitin [MeSH concept]
- amitriptylin-neuraxpharm [MeSH concept]
- amitriptyline [MeSH concept]
- amitriptyline hydrochloride [MeSH concept]
- amitrol [MeSH concept]
- anapsique [MeSH concept]
- damilen [MeSH concept]
- domical [MeSH concept]
- laroxyl [MeSH concept]
- lentizol [MeSH concept]
- novoprotect [MeSH concept]
- saroten [MeSH concept]
- sarotex [MeSH concept]
- syneudon [MeSH concept]
- triptafen [MeSH concept]
- tryptine [MeSH concept]
- tryptizol [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-chloroamitriptyline [MeSH Supplementary Concept]
- 10-hydroxyamitriptyline [MeSH Supplementary Concept]
- 10-hydroxyamitriptyline-N-glucuronide [MeSH Supplementary Concept]
- 5-(3-dimethylaminoprop-1-enylidene)-5H-dibenzo(a,d)cycloheptene maleate [MeSH Supplementary Concept]
- N-phenylethyl amitriptyline [MeSH Supplementary Concept]
- OMS 103HP [MeSH Supplementary Concept]
- amitriptyline N-glucuronide [MeSH Supplementary Concept]
- amitriptyline N-oxide [MeSH Supplementary Concept]
- amitriptyline, chlordiazepoxide drug combination [MeSH Supplementary Concept]
- amitriptyline, perphenazine drug combination [MeSH Supplementary Concept]
- benzaprinoxide [MeSH Supplementary Concept]
- cotriptyline [MeSH Supplementary Concept]
- cyclobenzaprine [MeSH Supplementary Concept]
- dimethylprotriptyline [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- adrenergic uptake inhibitors [MeSH Descriptor]
- analgesics, non-narcotic [MeSH Descriptor]
- antidepressive agents, tricyclic [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing amitriptyline (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Amitriptyline [NCIt concept]
- Amitriptyline [LOINC component]
- Amitriptyline (substance) [SNOMED CT concept]
- Product containing amitriptyline (medicinal product) [SNOMED CT concept]
- amitriptyline [ATC Code]
- amitriptyline [Substance BNPC]
- amitriptyline [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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