T-Lymphoma Invasion and Metastasis-inducing Protein 1

Preferred Label : T-Lymphoma Invasion and Metastasis-inducing Protein 1;

MeSH definition : A Rho guanine nucleotide exchange factor that consists of two pleckstrin homology domains flanking central Ras-binding, Dbl-homology (DH) and PDZ domains. It stimulates GTP-GDP exchange of rho-like GTPases such as RAC1 PROTEIN; CDC42 PROTEIN; and RHOA PROTEIN, and functions to link extracellular signals to remodeling of the CYTOSKELETON for CELL ADHESION and CELL MOVEMENT.;

MeSH synonym : T Lymphoma Invasion and Metastasis inducing Protein 1; TIAM-1 Protein; TIAM 1 Protein; TIAM1 Protein;

Details

Origin ID

D000075684;

UMLS CUI

C0919491;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- T-Lymphoma Invasion and Metastasis-inducing Protein 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- TIAM-1 protein, C elegans [MeSH Supplementary Concept]
- TIAM1 protein, human [MeSH Supplementary Concept]
- Tiam1 protein, mouse [MeSH Supplementary Concept]
- Tiam1 protein, rat [MeSH Supplementary Concept]
See also
- Pleckstrin Homology Domains [MeSH Descriptor]
- pdz domains [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- T-Lymphoma Invasion and Metastasis-Inducing Protein 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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