Preferred Label : pdz domains;
MeSH definition : Protein interaction domains of about 70-90 amino acid residues, named after a common
structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains
are involved in the recruitment and interaction of proteins, and aid the formation
of protein scaffolds and signaling networks. This is achieved by sequence-specific
binding between a PDZ domain in one protein and a PDZ motif in another protein.;
MeSH synonym : domain, pdz; domain, pdz interaction; domain, psd95-dlg-zo1; domains, pdz; domains, pdz interaction; glgf repeats domain; glgf repeats domains; interaction domain, pdz; interaction domains, pdz; pdz domain; pdz interaction domains; psd95 dlg zo1 domains; repeats domains, glgf; dhr domain; pdz interaction domain; psd95-dlg-zo1 domains; domains, psd95-dlg-zo1; psd95-dlg-zo1 domain; dlg homology repeats domains; domain, glgf repeats; domains, glgf repeats; repeats domain, glgf; dhr domains; domain, dhr; domains, dhr;
Origin ID : D054731;
UMLS CUI : C1956036;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Indexing information
- Record concept(s)
- See also
- Semantic type(s)
- UMLS correspondences (same concept)
Protein interaction domains of about 70-90 amino acid residues, named after a common
structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains
are involved in the recruitment and interaction of proteins, and aid the formation
of protein scaffolds and signaling networks. This is achieved by sequence-specific
binding between a PDZ domain in one protein and a PDZ motif in another protein.
