AAA Domain - CISMeF

Preferred Label : AAA Domain;

MeSH definition : An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase subdomain with an alpha-beta-alpha conformation, and a less-conserved C-terminal subdomain with an all alpha conformation. The N-terminal subdomain includes Walker A and Walker B motifs which function in ATP binding and hydrolysis.;

MeSH synonym : AAA Modules; AAA Module; Module, AAA ; Modules, AAA ; AAA Domain; AAA Domains; Domain, AAA ; Domains, AAA ; AAA Modules; AAA Module; Module, AAA; Modules, AAA; AAA Domains; Domain, AAA; Domains, AAA;

DeCS synonym : Walker Motifs; A-Loop; Walker B Motif; Walker A Motif;

MeSH hyponym : Motifs, Walker; Walker Motif; Motif, Walker; P-Loop; P Loop; P-Loops; B Motif, Walker; Motif, Walker B; A Motif, Walker; Motif, Walker A;

Related MeSH term : A Loop; A-Loops;

Wikipedia link : https://en.wikipedia.org/wiki/Walker motif;

Details

Origin ID

D000074182;

UMLS CUI

C4505201;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Loop (qualifier value) [SNOMED CT concept]
Record concept(s)
- A-Loop [MeSH concept]
- AAA Domain [MeSH concept]
- Walker A Motif [MeSH concept]
- Walker B Motif [MeSH concept]
- Walker Motifs [MeSH concept]
See also
- ATPases Associated with Diverse Cellular Activities [MeSH Descriptor]
- Katanin [MeSH Descriptor]
- Spastin [MeSH Descriptor]
- origin recognition complex [MeSH Descriptor]
Semantic type(s)
- Amino Acid Sequence [UMLS semantic type]

Keyword's position in hierarchy(ies) :

Main resources

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