MeSH definition : An AAA ATPase consisting of the 60 kDa ATPase subunit (p60 subunit A1) which severs
MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets the
enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES
to allow depolymerization and poleward motion of chromosomes. It is also a regulator
of microtubule dynamics in NEURONAL OUTGROWTH.; An enzyme (AAA ATPase) consisting of the 60 kDa ATPase subunit (p60 subunit A1) which
severs MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets
the enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES
to allow depolymerization and poleward motion of chromosomes. It is also a regulator
of microtubule dynamics in NEURONAL OUTGROWTH.;
Registry Number MeSH : EC 3.6.4.3;
Wikipedia link : https://en.wikipedia.org/wiki/Katanin;
An AAA ATPase consisting of the 60 kDa ATPase subunit (p60 subunit A1) which severs
MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets the
enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES
to allow depolymerization and poleward motion of chromosomes. It is also a regulator
of microtubule dynamics in NEURONAL OUTGROWTH. An enzyme (AAA ATPase) consisting of the 60 kDa ATPase subunit (p60 subunit A1) which
severs MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets
the enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES
to allow depolymerization and poleward motion of chromosomes. It is also a regulator
of microtubule dynamics in NEURONAL OUTGROWTH.
Allowable qualifiers