Preferred Label : ATP Binding Cassette Transporter, Subfamily G, Member 2;
MeSH definition : An ATP binding cassette transporter, sub-family G protein that functions as a high
capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of
many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE.
It functions as a homodimer and is expressed by cells in a variety of organs, as well
as by NEOPLASTIC STEM CELLS.; ATP-binding cassette transporter, sub-family G protein that functions as a high capacity
UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs.
Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions
as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC
STEM CELLS.;
MeSH synonym : ABCG2 Transporter; ABCG2 Protein; CD338 Antigen; ATP Binding Cassette Transporter, Sub-Family G, Member 2;
CISMeF synonym : Antigen, CD338;
Origin ID : D000070997;
UMLS CUI : C4255314;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
An ATP binding cassette transporter, sub-family G protein that functions as a high
capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of
many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE.
It functions as a homodimer and is expressed by cells in a variety of organs, as well
as by NEOPLASTIC STEM CELLS.
ATP-binding cassette transporter, sub-family G protein that functions as a high capacity
UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs.
Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions
as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC
STEM CELLS.
