Preferred Label : Dimethyl Fumarate;

MeSH definition : A fumarate derivative that is used as a DERMATOLOGIC AGENT in the treatment of PSORIASIS and SKIN DISEASES. It also may be used as an IMMUNOSUPPRESSIVE AGENT in the treatment of MULTIPLE SCLEROSIS.;

MeSH synonym : Fumarate, Dimethyl; 2-butenedioic acid, (2E)-, dimethyl ester; Dimethylfumarate;

MeSH hyponym : BG 12 compound; FAG 201; BG 00012; fumaderm; tecfidera; 00012, BG; BG00012; BG-00012; 201, FAG; FAG201; FAG-201; 12 compound, BG; compound, BG 12; BG12 compound; compound, BG12; BG-12 compound;

MeSH Related Number : 624-49-7 (dimethyl fumarate);

Wikipedia link : https://en.wikipedia.org/wiki/Fumaderm;

Codes EINECS : 210-849-0;

Is substance : O;

UNII : FO2303MNI2;

Details


Main resources

You can consult :

A fumarate derivative that is used as a DERMATOLOGIC AGENT in the treatment of PSORIASIS and SKIN DISEASES. It also may be used as an IMMUNOSUPPRESSIVE AGENT in the treatment of MULTIPLE SCLEROSIS.

https://ansm.sante.fr/actualites/abrogation-de-certaines-autorisations-de-mise-sur-le-marche-de-generiques-de-tecfidera
2024
false
false
false
France
French
drug information
drugs, generic
Dimethyl Fumarate
legislation, pharmacy
europe
drug approval
dimethyl fumarate
legislation, drug

---
https://www.ema.europa.eu/en/medicines/human/EPAR/dimethyl-fumarate-polpharma
2022
false
false
false
Netherlands
French
English
Dimethyl Fumarate
Dimethyl Fumarate
dimethyl fumarate
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drugs, generic
administration, oral

---
https://www.ema.europa.eu/en/medicines/human/EPAR/dimethyl-fumarate-mylan
2022
false
false
false
Netherlands
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
Dimethyl Fumarate
Dimethyl Fumarate
dimethyl fumarate
drugs, generic
administration, oral
drug approval
europe

---
https://www.ema.europa.eu/en/medicines/human/EPAR/dimethyl-fumarate-neuraxpharm
2022
false
false
false
Netherlands
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
Dimethyl Fumarate
Dimethyl Fumarate
dimethyl fumarate
drugs, generic
administration, oral
drug approval
europe

---
https://www.has-sante.fr/jcms/p_3266575/fr/tecfidera-dimethyle-fumarate
2021
false
false
false
France
treatment outcome
insurance, health, reimbursement
dimethyl fumarate
administration, oral
adult
multiple sclerosis, relapsing-remitting
Dimethyl Fumarate
leukoencephalopathy, progressive multifocal
evaluation of the transparency committee
Dimethyl Fumarate

---
https://ansm.sante.fr/informations-de-securite/tecfidera-et-risque-de-leucoencephalopathie-multifocale-progressive-actualisation-des-recommandations
2020
false
false
false
France
French
guidelines for drug use
pharmacovigilance note
leukoencephalopathy, progressive multifocal
Dimethyl Fumarate
Dimethyl Fumarate
lymphopenia
drug monitoring
dimethyl fumarate
lymphocytes

---
https://www.has-sante.fr/jcms/p_3082103/fr/skilarence
2019
false
false
false
France
Dimethyl Fumarate
administration, oral
insurance, health, reimbursement
treatment outcome
psoriasis
adult
dermatologic agents
dimethyl fumarate
evaluation of the transparency committee

---
https://www.ema.europa.eu/medicines/human/EPAR/Skilarence
2017
false
false
false
United Kingdom
French
English
syndication feed
summary of product characteristics
package leaflet
drug evaluation
Dimethyl Fumarate
drug approval
europe
treatment outcome
psoriasis
dermatologic agents
dermatologic agents
administration, oral
tablets
immunosuppressive agents
immunosuppressive agents
adult
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
antipsoriatics for systemic use
Dimethyl Fumarate

---
Summary Safety Review - TECFIDERA (Dimethyl Fumarate) - Serious allergic reactions including skin reactions and anaphylaxis
http://www.hc-sc.gc.ca/dhp-mps/medeff/reviews-examens/tecfidera-fra.php
2015
false
false
false
Canada
French
English
pharmacovigilance note
administration, oral
multiple sclerosis
risk assessment
drug hypersensitivity
angioedema
anaphylaxis
Dimethyl Fumarate
dimethyl fumarate

---
https://www.cochrane.org/fr/CD011076/
2015
false
false
false
France
United Kingdom
French
meta-analysis
multiple sclerosis
treatment outcome
administration, oral
drug administration schedule
french abstract
Dimethyl Fumarate
Dimethyl Fumarate

---
ECFIDERA (dimethyl fumarate) - Risk of Rare Brain Condition Known as Progressive Multifocal Leukoencephalopathy (PML) - For Health Professionals
http://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2015/43625a-fra.php
http://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2015/43627a-fra.php
2015
false
false
false
Canada
French
English
pharmacovigilance note
multiple sclerosis, relapsing-remitting
risk
leukoencephalopathy, progressive multifocal
lymphopenia
drug monitoring
immunologic factors
Dimethyl Fumarate
dimethyl fumarate

---
https://www.ema.europa.eu/medicines/human/EPAR/Tecfidera
2014
false
United Kingdom
French
English
drug approval
europe
treatment outcome
administration, oral
adult
multiple sclerosis, relapsing-remitting
aged
drug interactions
pregnancy
breast feeding
immunologic factors
immunologic factors
clinical trials as topic
drug evaluation, preclinical
drug evaluation
summary of product characteristics
package leaflet
syndication feed
Dimethyl Fumarate
Dimethyl Fumarate
dimethyl fumarate

---
http://www.has-sante.fr/portail/jcms/c_1743058/fr/tecfidera
2014
false
France
French
administration, oral
Delayed-Action preparations
adjuvants, immunologic
adjuvants, immunologic
multiple sclerosis, relapsing-remitting
adult
treatment outcome
insurance, health, reimbursement
evaluation of the transparency committee
Dimethyl Fumarate
Dimethyl Fumarate
dimethyl fumarate

---
Summary Basis of Decision (SBD) for Tecfidera
Dimethyl fumarate, 120 mg, capsule, oral
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailTwo.php?lang=fr&linkID=SBD00195
2013
false
Canada
French
English
Dimethyl Fumarate
Dimethyl Fumarate
drug information
drug approval
canada
administration, oral
treatment outcome
immunosuppressive agents
immunosuppressive agents
clinical trials, phase iii as topic
randomized controlled trials as topic
multiple sclerosis, relapsing-remitting
dimethyl fumarate

---
https://centres-antipoison.net/wp-content/uploads/2017/08/Rapport_CCTV_Dimethylfumarate_Mars_2012.pdf
2012
false
true
false
France
Dimethyl Fumarate
Dimethyl Fumarate
Dimethyl Fumarate
Dimethyl Fumarate
dermatitis, contact
dermatitis, contact
technical report

---
https://solidarites-sante.gouv.fr/sante-et-environnement/risques-microbiologiques-physiques-et-chimiques/article/dimethylfumarate
2012
false
France
French
Dimethyl Fumarate
popular works
europe
dermatitis, allergic contact
consumer product safety
antifungal agents
commerce
legislation, drug
shoes
interior design and furnishings

---
https://centres-antipoison.net/wp-content/uploads/2017/08/Rapport_CCTV_DMFu_2009-2010_VFINALE.pdf
2011
false
France
French
Dimethyl Fumarate
Dimethyl Fumarate
Dimethyl Fumarate
environmental exposure
drug eruptions
france
antifungal agents
europe
retrospective studies
drug eruptions
technical report

---
https://www.anses.fr/fr/system/files/CHIM2009sa0327.pdf
2011
false
France
French
guidelines
Dimethyl Fumarate
occupational exposure
environmental exposure

---
https://centres-antipoison.net/wp-content/uploads/2017/08/Rapport_CCTV_DMFU_2009.pdf
2009
false
France
French
technical report
Dimethyl Fumarate
Dimethyl Fumarate
Dimethyl Fumarate
risk
ethylene glycols
diethylene glycol maleate
dioctyl maleate
environmental exposure
occupational exposure
europe
dermatitis, contact
sentinel surveillance
data collection
france
eczema
administration, oral
administration, cutaneous
diethyl fumarate
ethyl fumarate
dimethyl maleate
maleates
diethyl maleate
dibutyl maleate

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10/06/2024


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