Natalizumab - CISMeF

Preferred Label : Natalizumab;

MeSH definition : A humanized monoclonal immunoglobulin G4 antibody to human INTEGRIN ALPHA4 that binds to the alpha4 subunit of INTEGRIN ALPHA4BETA1 and integrin alpha4beta7. It is used as an IMMUNOLOGIC FACTOR in the treatment of RELAPSING-REMITTING MULTIPLE SCLEROSIS and CROHN'S DISEASE.;

MeSH hyponym : antegren; tysabri;

Wikipedia link : https://en.wikipedia.org/wiki/Natalizumab;

Is substance : O;

Details

Origin ID

D000069442;

UMLS CUI

C1172734;

ATC code(s)
- natalizumab [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Exact mapping(s) to DCI
- natalizumab [International Nonproprietary Name]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- antegren [MeSH concept]
- natalizumab [MeSH concept]
- tysabri [MeSH concept]
See also
- integrin alpha4 [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing natalizumab (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Natalizumab [NCIt concept]
- Natalizumab [LOINC component]
- Natalizumab (substance) [SNOMED CT concept]
- Product containing natalizumab (medicinal product) [SNOMED CT concept]
- natalizumab [ATC Code]
- natalizumab [International Nonproprietary Name]
Validated automatic mappings to BTNT
- natalizumab [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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