Preferred Label : Duloxetine Hydrochloride;

MeSH definition : A thiophene derivative and selective NEUROTRANSMITTER UPTAKE INHIBITOR for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC, and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.;

MeSH synonym : Hydrochloride, Duloxetine; Duloxetine HCl; HCl, Duloxetine;

MeSH Hyperonym : duloxetine; N-methyl-3-(1-naphthalenyloxy)-3-(2-thiophene)propanamide; N-methyl-3-(1-naphthalenyloxy)-2-thiophenepropanamine;

MeSH hyponym : cymbalta; LY 248686; LY 227942; duloxetine, ( )-isomer; Duloxetine Ethanedioate (1:1), ( -)-isomer - T353987; LY-248686; LY248686; LY-227942; LY227942;

MeSH Related Number : 116539-58-3; 116539-59-4; 116539-60-7; 118625-29-9; 136434-34-9 (Duloxetine Hydrochloride); O5TNM5N07U;

Is substance : O;

UNII : 9044SC542W;

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A thiophene derivative and selective NEUROTRANSMITTER UPTAKE INHIBITOR for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC, and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.

http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=60457719
2021
false
false
false
France
French
Duloxetine Hydrochloride
summary of product characteristics
package leaflet

---
https://www.inesss.qc.ca/publications/repertoire-des-publications/publication/usage-de-la-duloxetine.html
2020
Canada
guidelines for drug use
Duloxetine Hydrochloride
duloxetine

---
http://www.has-sante.fr/portail/jcms/c_2620138/fr/cymbalta
2016
false
France
French
Duloxetine Hydrochloride
Duloxetine Hydrochloride
Generalized Anxiety Disorder
anxiety disorders
insurance, health, reimbursement
Serotonin and Noradrenaline Reuptake Inhibitors
Serotonin and Noradrenaline Reuptake Inhibitors
antidepressive agents
antidepressive agents
diabetic neuropathies
depressive disorder, major
adult
treatment outcome
aged
drug evaluation
duloxetine
evaluation of the transparency committee

---
http://www.lecrat.eu/?s=Etat+des+connaissances+sur+la+dulox%C3%A9tine
2016
false
false
false
false
France
French
drug information
pregnancy
duloxetine
infant, newborn
infant, newborn, diseases
prenatal exposure delayed effects
Selective Serotonin Reuptake Inhibitors
Selective Serotonin Reuptake Inhibitors
Duloxetine Hydrochloride
Duloxetine Hydrochloride

---
http://www.lecrat.eu/?s=Dulox%C3%A9tine+dans+la+douleur+neuropathique+-+Grossesse+et+allaitement
2016
false
false
false
false
France
French
drug information
duloxetine
Duloxetine Hydrochloride
neuralgia
pregnancy
breast feeding

---
http://www.lecrat.eu/?s=Dulox%C3%A9tine+dans+la+d%C3%A9pression+-+Grossesse+et+allaitement
2016
false
false
false
false
France
French
drug information
duloxetine
antidepressive agents
Selective Serotonin Reuptake Inhibitors
Duloxetine Hydrochloride
breast feeding
depressive disorder, major
pregnancy

---
https://www.ema.europa.eu/medicines/human/EPAR/duloxetine-zentiva
2015
true
United Kingdom
English
French
europe
anxiety disorders
Generalized Anxiety Disorder
syndication feed
drugs, generic
drug evaluation
Duloxetine Hydrochloride
Duloxetine Hydrochloride
Selective Serotonin Reuptake Inhibitors
drug evaluation, preclinical
drug approval
diabetic neuropathies
antidepressive agents
depressive disorder, major
adult
Selective Serotonin Reuptake Inhibitors
adrenergic uptake inhibitors
treatment outcome
drug evaluation
Delayed-Action preparations
administration, oral
aged
drug interactions
pregnancy
breast feeding
antidepressive agents
adrenergic uptake inhibitors
duloxetine
summary of product characteristics
package leaflet

---
https://www.ema.europa.eu/medicines/human/EPAR/duloxetine-lilly
2015
false
United Kingdom
English
French
europe
anxiety disorders
Generalized Anxiety Disorder
syndication feed
Duloxetine Hydrochloride
Duloxetine Hydrochloride
Selective Serotonin Reuptake Inhibitors
drug evaluation, preclinical
drug approval
diabetic neuropathies
antidepressive agents
depressive disorder, major
adult
Selective Serotonin Reuptake Inhibitors
adrenergic uptake inhibitors
treatment outcome
drug evaluation
Delayed-Action preparations
administration, oral
aged
drug interactions
pregnancy
breast feeding
antidepressive agents
adrenergic uptake inhibitors
duloxetine
summary of product characteristics
drug evaluation
package leaflet

---
https://www.ema.europa.eu/medicines/human/EPAR/duloxetine-mylan
2015
false
United Kingdom
English
French
europe
anxiety disorders
Generalized Anxiety Disorder
syndication feed
drugs, generic
Duloxetine Hydrochloride
Duloxetine Hydrochloride
Selective Serotonin Reuptake Inhibitors
drug evaluation, preclinical
drug approval
diabetic neuropathies
antidepressive agents
depressive disorder, major
adult
Selective Serotonin Reuptake Inhibitors
adrenergic uptake inhibitors
treatment outcome
drug evaluation
Delayed-Action preparations
administration, oral
aged
drug interactions
pregnancy
breast feeding
antidepressive agents
adrenergic uptake inhibitors
duloxetine
summary of product characteristics
package leaflet

---
https://www.ema.europa.eu/medicines/human/EPAR/Xeristar
2014
false
United Kingdom
English
French
anxiety disorders
Generalized Anxiety Disorder
syndication feed
Duloxetine Hydrochloride
Duloxetine Hydrochloride
antidepressive agents
depressive disorder, major
diabetic neuropathies
adult
Selective Serotonin Reuptake Inhibitors
adrenergic uptake inhibitors
treatment outcome
drug evaluation
capsules
Delayed-Action preparations
aged
drug interactions
pregnancy
breast feeding
adrenergic uptake inhibitors
antidepressive agents
Selective Serotonin Reuptake Inhibitors
drug evaluation, preclinical
drug approval
drug labeling
duloxetine
drug evaluation
summary of product characteristics
package leaflet

---
https://www.minerva-ebp.be/FR/Article/1036
2014
true
false
Belgium
French
critical appraisal or critical reading
duloxetine
Duloxetine Hydrochloride
Duloxetine Hydrochloride
chronic pain
diabetic neuropathies
treatment outcome
fibromyalgia

---
https://www.ema.europa.eu/medicines/human/EPAR/Cymbalta
2012
false
United Kingdom
English
French
syndication feed
Duloxetine Hydrochloride
Duloxetine Hydrochloride
Serotonin and Noradrenaline Reuptake Inhibitors
Serotonin and Noradrenaline Reuptake Inhibitors
drug evaluation, preclinical
drug approval
drug labeling
diabetic neuropathies
antidepressive agents
depressive disorder, major
adult
treatment outcome
drug evaluation
Delayed-Action preparations
administration, oral
aged
drug interactions
pregnancy
breast feeding
antidepressive agents
duloxetine
summary of product characteristics
drug evaluation
package leaflet

---
https://www.ema.europa.eu/medicines/human/EPAR/Ariclaim
2012
false
United Kingdom
English
French
syndication feed
Duloxetine Hydrochloride
Duloxetine Hydrochloride
adrenergic uptake inhibitors
treatment outcome
drug evaluation
capsules
Delayed-Action preparations
adult
drug interactions
adrenergic uptake inhibitors
Selective Serotonin Reuptake Inhibitors
urinary incontinence, stress
pregnancy
breast feeding
Selective Serotonin Reuptake Inhibitors
drug evaluation, preclinical
drug labeling
drug approval
duloxetine
drug evaluation
summary of product characteristics
package leaflet

---
https://rmlg.uliege.be/article/2377
2012
false
Belgium
French
Duloxetine Hydrochloride
Aripiprazole
depressive disorder, major
journal article
case reports
antidepressive agents
antipsychotic agents
drug therapy, combination
depressive disorder, Treatment-Resistant
chronic disease

---
https://www.ema.europa.eu/medicines/human/EPAR/Yentreve
2011
false
United Kingdom
French
English
syndication feed
Duloxetine Hydrochloride
drug approval
europe
Selective Serotonin Reuptake Inhibitors
adrenergic uptake inhibitors
treatment outcome
drug evaluation
urinary incontinence, stress
duloxetine
summary of product characteristics
package leaflet
drug evaluation

---
http://www.cochrane.org/fr/CD007115
2011
false
United Kingdom
France
French
Duloxetine Hydrochloride
meta-analysis
chronic pain
diabetic neuropathies
treatment outcome
fibromyalgia
french abstract

---
https://www.ema.europa.eu/medicines/human/EPAR/duloxetine-boehringer-ingelheim
2010
false
United Kingdom
French
syndication feed
Duloxetine Hydrochloride
Duloxetine Hydrochloride
Selective Serotonin Reuptake Inhibitors
drug approval
treatment outcome
adrenergic uptake inhibitors
drug labeling
capsules
administration, oral
tablets, enteric-coated
urinary incontinence, stress
diabetic neuropathies
adrenergic uptake inhibitors
Selective Serotonin Reuptake Inhibitors
adult
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
duloxetine
package leaflet
summary of product characteristics
drug evaluation

---
https://www.minerva-ebp.be/fr/article/451
2009
false
minerva-ebm.be
Belgium
French
Duloxetine Hydrochloride
antidepressive agents
adrenergic uptake inhibitors
fibromyalgia
critical appraisal or critical reading

---
https://cadth.ca/sites/default/files/cdr/complete/cdr_complete_Cymbalta-DPN_August-14-2008-fr.pdf
2008
false
Canada
French
Duloxetine Hydrochloride
canada
insurance, health, reimbursement
diabetic neuropathies
capsules
Delayed-Action preparations
administration, oral
drug costs
treatment outcome
adrenergic uptake inhibitors
Selective Serotonin Reuptake Inhibitors
Cost-Benefit analysis
duloxetine
drug evaluation

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=68263545
2008
false
France
French
Duloxetine Hydrochloride
capsules
tablets, enteric-coated
administration, oral
antidepressive agents
duloxetine
drug information

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=66852477
2008
false
France
French
Duloxetine Hydrochloride
capsules
tablets, enteric-coated
administration, oral
duloxetine
drug information

---
https://cadth.ca/sites/default/files/cdr/complete/cdr_complete_Cymbalta-MDD_August-14-2008-fr.pdf
2008
false
Canada
French
Duloxetine Hydrochloride
Serotonin and Noradrenaline Reuptake Inhibitors
canada
insurance, health, reimbursement
antidepressive agents
tablets
administration, oral
adult
depressive disorder, major
drug costs
Cost-Benefit analysis
treatment outcome
duloxetine
drug evaluation

---
http://www.has-sante.fr/portail/jcms/c_523247/cymbalta
http://www.has-sante.fr/portail/upload/docs/application/pdf/ct-2319_cymbalta_.pdf
http://www.has-sante.fr/portail/upload/docs/application/pdf/2010-06/cymbalta_ct_2319.pdf
2007
false
France
French
English
Duloxetine Hydrochloride
evaluation of the transparency committee
administration, oral
antidepressive agents
insurance, health, reimbursement
duloxetine
depressive disorder, major
diabetic neuropathies
adult
aged
treatment outcome

---
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20/05/2024


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