ICD-11 code : 4B24;
Preferred Label : Graft-versus-host disease;
ICD-11 definition : Graft-versus-host disease (GVHD) occurs when lymphoid cells from an immunocompetent
donor are introduced into a histo-incompatible recipient incapable of rejecting them.
This usually occurs as a result of haematopoietic stem cell transplantation. The main
targets attacked by the donor lymphocytes are the recipient's skin, gastrointestinal
tract and liver. Acute GVHD, normally occurring within the first 100 days following
transplantation, has a high mortality. The acute phase may be followed by chronic
GVHD, which can also arise de novo. This usually presents as a lichenoid rash but
can develop into a severe fibrosing disease affecting skin, lungs and liver.;
ICD-11 synonym : GVH - [graft-versus-host] reaction; GVH reaction; graft-versus-host reaction or disease; GVH disease; GVHD - [graft-versus-host disease]; GVH - [graft-versus-host] disease;
ICD-11 acronym : GVHD;
ICD-11 "other" category code : 4B24.Y;
ICD-11 "unspecified" category code : 4B24.Z;
Origin ID : 437372167;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- ICD-10 Mapping
Graft-versus-host disease (GVHD) occurs when lymphoid cells from an immunocompetent
donor are introduced into a histo-incompatible recipient incapable of rejecting them.
This usually occurs as a result of haematopoietic stem cell transplantation. The main
targets attacked by the donor lymphocytes are the recipient's skin, gastrointestinal
tract and liver. Acute GVHD, normally occurring within the first 100 days following
transplantation, has a high mortality. The acute phase may be followed by chronic
GVHD, which can also arise de novo. This usually presents as a lichenoid rash but
can develop into a severe fibrosing disease affecting skin, lungs and liver.
