Preferred Label : Graft Versus Host Disease;
NCIt synonyms : Graft-Versus-Host-Disease; Graft vs Host Disease; Runt Disease; Graft Vs. Host Disease;
NCIt related terms : graft-versus-host disease; GvHD;
NCIt definition : A reaction, which may be fatal, in an immunocompromised subject (host) who has received
an antigenically incompatible tissue transplant (graft) from an immunocompetent donor.
The reaction is secondary to the activation of the transplanted cells against those
host tissues that express an antigen not expressed by the donor, and is seen most
commonly following bone marrow transplantation; acute disease is seen after 5-40 days,
and chronic disease occurs weeks to months after transplantation.;
Alternative definition : NCI-GLOSS: A disease caused when cells from a donated stem cell graft attack the normal
tissue of the transplant patient. Symptoms include jaundice, skin rash or blisters,
a dry mouth, or dry eyes.; NICHD: A reaction, which may be fatal, in an immunocompromised subject (host) who
has received an antigenically incompatible tissue transplant (graft) from an immunocompetent
donor. The reaction is secondary to the activation of the transplanted cells against
those host tissues that express an antigen not expressed by the donor, and is seen
most commonly following stem cell transplantation; acute disease is seen after 5-40
days, and chronic disease occurs weeks to months after transplantation.;
Codes from synonyms : CDR0000045703; CDR0000046376;
Origin ID : C3063;
UMLS CUI : C0018133;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
False automatic mappings
Semantic type(s)
UMLS correspondences (same concept)
concept_is_in_subset
disease_has_finding