core binding factor alpha 1 subunit

Preferred Label : core binding factor alpha 1 subunit;

MeSH definition : A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.;

MeSH synonym : cbfa 1 protein; osf2 transcription factor; sef1 protein; sl3 3 enhancer factor 1; aml3 transcription factor; cbfa-1 protein; cbfa1 protein; sl3-3 enhancer factor 1; cbfalpha1 protein; pebp2alphaa protein; runx2 protein; acute myeloid leukemia 3 protein; cbfalpha runt domain transcription factor 1;

MeSH annotation : see SCR for organism-specific terms;

Is substance : O;

Details

Origin ID

D050659;

UMLS CUI

C0539345;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Runt-Related Transcription Factor 2 [NCIt concept]
Record concept(s)
- core binding factor alpha 1 subunit [MeSH concept]
Related MeSH Supplementary Concept(s)
- RUNX2 protein, human [MeSH Supplementary Concept]
- Runx2 protein, mouse [MeSH Supplementary Concept]
- Runx2 protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Runt-Related Transcription Factor 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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