Preferred Label : drug incompatibility;

MeSH definition : The quality of not being miscible with another given substance without a chemical change. One drug is not of suitable composition to be combined or mixed with another agent or substance. The incompatibility usually results in an undesirable reaction, including chemical alteration or destruction. (Dorland, 27th ed; Stedman, 25th ed);

MeSH synonym : drug incompatibilities; incompatibilities, drug; incompatibility, drug;

DeCS synonym : Incompatible Drugs; Drugs, Opposite;

MeSH annotation : one drug is not of suitable composition to be combined or mixed with another: do not confuse with DRUG INTERACTIONS, the action of one drug on the metab, effect or tox of another; IM when general; NIM when with specific drug; no qualif; one drug is not of suitable composition to be combined or mixed with another: do not confuse with DRUG INTERACTIONS, the action of one drug on the metab, effect or tox of another; IM when general; NIM when with specific drug;

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The quality of not being miscible with another given substance without a chemical change. One drug is not of suitable composition to be combined or mixed with another agent or substance. The incompatibility usually results in an undesirable reaction, including chemical alteration or destruction. (Dorland, 27th ed; Stedman, 25th ed)

https://pharmactuel.com/index.php/pharmactuel/article/view/1294
2019
false
false
false
Canada
drug incompatibility
infusions, intravenous
journal article
ketamine
intensive care
Levosimendan
critical care
dexmedetomidine
Simendan

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http://www.pharmactuel.com/index.php/pharmactuel/article/view/1129
2017
false
false
false
Canada
French
journal article
Caffeine citrate 20mg/mL injection solution ampule (product)
drug incompatibility
infusions, intravenous
infant, premature
infant, newborn
apnea
Apnea of Prematurity
respiratory stimulants
caffeine citrate
caffeine
citrates

---
http://www.pharmactuel.com/index.php/pharmactuel/article/view/264
2015
false
false
false
Canada
French
journal article
drug incompatibility
infusions, intravenous
intensive care units

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Primene 10% Amino Acid Solution, 250 mL - Compatibility Issue with Trace Elements - Update
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2015/55942a-fra.php
2015
false
false
false
Canada
French
English
parenteral nutrition solutions
amino acids
drug incompatibility
trace elements
pharmacovigilance note
infant
child
infusions, intravenous
parenteral nutrition, total
amino acids

---
Primene 10% Amino Acid Injection, 250 mL, Pharmacy Bulk Pack - Compatibility Issue with Trace Elements
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2015/52883a-fra.php
2015
false
false
false
Canada
French
English
pharmacovigilance note
trace elements
parenteral nutrition solutions
drug incompatibility
amino acids
infusions, intravenous
canada
infant
child
drug therapy, combination
amino acids

---
http://www.pharmactuel.com/index.php/pharmactuel/article/view/891
2013
false
Canada
French
journal article
drug incompatibility
naloxone
injections, intravenous
naloxone

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http://www.stabilis.org/
France
French
drug stability
injections
pharmaceutical preparations
drug incompatibility
database
databases, pharmaceutical

---
https://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2008/14497a-fra.php
2008
Canada
English
French
antibiotic therapy
Contraindications, Procedure
ceftriaxone
injections, intravenous
drug incompatibility
pharmaceutical solutions
calcium compounds
chemical precipitation
drug interactions
infant, newborn
infant
canada
anti-bacterial agents
calcium
pharmacovigilance note
Contraindications, Drug

---
https://www.hug.ch/sites/interhug/files/structures/pharmacie/infos-medic/cappinfo/cappinfo40.pdf
2006
Switzerland
French
infusions, parenteral
drug incompatibility
risk factors
drug information
journal article

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07/06/2025


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