Simendan - CISMeF

Preferred Label : Simendan;

MeSH definition : A hydrazone and pyridazine derivative; the levo-form is a phosphodiesterase III inhibitor, calcium-sensitizing agent, and inotropic agent that is used in the treatment of HEART FAILURE.;

MeSH synonym : ((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile;

MeSH hyponym : OR-1259; OR 1855;

MeSH CAS label : Propanedinitrile, 2-(2-(4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazinylidene)-;

MeSH Related Number : 131741-08-7 (Simendan); C6T4514L4E;

UNII : 349552KRHK;

Details

Origin ID

D000077464;

UMLS CUI

C0287806;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Levosimendan (substance) [SNOMED CT concept]
- Product containing levosimendan (medicinal product) [SNOMED CT concept]
- levosimendan [ATC Code]
Currated CISMeF NLP mapping
- Simendan [NCIt concept]
- Simendan [SMS substance]
Pharmacological action(s)
- cardiotonic agents [MeSH Descriptor]
- phosphodiesterase 3 inhibitors [MeSH Descriptor]
- vasodilator agents [MeSH Descriptor]
Record concept(s)
- Levosimendan [MeSH concept]
- OR 1259 [MeSH concept]
- OR-1855 [MeSH concept]
- dextrosimendan [MeSH concept]
- simadax [MeSH concept]
- simendan [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Simendan [NCIt concept]

Keyword's position in hierarchy(ies) :

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