tacrolimus - CISMeF

Preferred Label : tacrolimus;

MeSH definition : A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.;

MeSH hyponym : anhydrous tacrolimus; FK-506; prograf; FR-900506; Prograft; FR 900506; FR900506; Tacrolimus, Anhydrous; Tacrolimus Anhydrous; Anhydrous, Tacrolimus; FK 506; FK506;

MeSH CAS label : 15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, monohydrate, (3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*))-;

MeSH Related Number : anhydrous tacrolimus; 109581-93-3 (Tacrolimus); Y5L2157C4J;

Registry Number MeSH : 109581-93-3;

Related CAS MeSH : Y5L2157C4J (Anhydrous tacrolimus);

Wikipedia link : https://en.wikipedia.org/wiki/Tacrolimus;

Is substance : O;

UNII : WM0HAQ4WNM;

InChIKey : NWJQLQGQZSIBAF-MLAUYUEBSA-N;

Details

Origin ID

D016559;

UMLS CUI

C0085149;

ATC code(s)
- tacrolimus [ATC Code]
ATC code(s)
- tacrolimus [ATC Code]
- tacrolimus [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- Blood tacrolimus level (procedure) [SNOMED CT concept]
- Tacrolimus measurement (procedure) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Tacrolimus [Substance BNPC]
- Tacrolimus [LOINC component]
- Tacrolimus [NCIt concept]
- Tacrolimus (substance) [SNOMED CT concept]
Indexing information
- FK506-binding protein 33, streptomyces chrysomallus [MeSH Supplementary Concept]
- FKBP-13 [MeSH Supplementary Concept]
- FKBP3 protein, human [MeSH Supplementary Concept]
- Fkbp3 protein, mouse [MeSH Supplementary Concept]
Pharmacological action(s)
- Calcineurin Inhibitors [MeSH Descriptor]
- immunosuppressive agents [MeSH Descriptor]
Record concept(s)
- FK-506 [MeSH concept]
- FR-900506 [MeSH concept]
- anhydrous tacrolimus [MeSH concept]
- prograf [MeSH concept]
- tacrolimus [MeSH concept]
Related MeSH Supplementary Concept(s)
- 13,15-O-bidesmethylascomycin [MeSH Supplementary Concept]
- 13-O-demethyl tacrolimus [MeSH Supplementary Concept]
- 13-O-desmethylascomycin [MeSH Supplementary Concept]
- 13-desmethoxy-13-methyl-FK 520 [MeSH Supplementary Concept]
- 15,31-desmethyl FK-506 [MeSH Supplementary Concept]
- 15-O-desmethyl-FK 520 [MeSH Supplementary Concept]
- 15-O-desmethylascomycin [MeSH Supplementary Concept]
- 15-desmethyl FK-506 [MeSH Supplementary Concept]
- 31-O-demethyl-FK506 [MeSH Supplementary Concept]
- 32-O-(1-hydroxyethylindol-5-yl)ascomycin [MeSH Supplementary Concept]
- 32-O-acetyltacrolimus [MeSH Supplementary Concept]
- 32-ascomycinyloxyacetic acid [MeSH Supplementary Concept]
- 9-deoxo-31-O-demethyl-FK506 [MeSH Supplementary Concept]
- A 85917 [MeSH Supplementary Concept]
- AP 1510 [MeSH Supplementary Concept]
- AP 1889 [MeSH Supplementary Concept]
- AP20187 [MeSH Supplementary Concept]
- AP23510 [MeSH Supplementary Concept]
- C24-deoxyascomycin [MeSH Supplementary Concept]
- CP 123369 [MeSH Supplementary Concept]
- FK 1012 [MeSH Supplementary Concept]
- FK 506-dextran conjugate [MeSH Supplementary Concept]
- FK1706 [MeSH Supplementary Concept]
- GPI 1485 [MeSH Supplementary Concept]
- JNJ460 [MeSH Supplementary Concept]
- L 683519 [MeSH Supplementary Concept]
- L 683590 [MeSH Supplementary Concept]
- L 685818 [MeSH Supplementary Concept]
- L 688617 [MeSH Supplementary Concept]
- L 733725 [MeSH Supplementary Concept]
- MLD 987 [MeSH Supplementary Concept]
- SDZ 281-240 [MeSH Supplementary Concept]
- antascomicin A [MeSH Supplementary Concept]
- antascomicin B [MeSH Supplementary Concept]
- antascomicin C [MeSH Supplementary Concept]
- antascomicin D [MeSH Supplementary Concept]
- antascomicin E [MeSH Supplementary Concept]
- dexamethasone-FK506 heterodimer [MeSH Supplementary Concept]
- immunomycin [MeSH Supplementary Concept]
- pimecrolimus [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing tacrolimus (medicinal product) [SNOMED CT concept]
- Tacrolimus [LOINC component]
- Tacrolimus [NCIt concept]
- Tacrolimus (substance) [SNOMED CT concept]
- tacrolimus [ATC Code]
- tacrolimus [ATC Code]

Keyword's position in hierarchy(ies) :

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