Preferred Label : cranial neural crest;
Uberon definition : neural crest cells (NCCs) originating in the anterior part of the developing embryo
and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs
migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into
various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues
of the face; these cells enter the pharyngeal pouches and arches where they give rise
to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts
of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute
to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte)
lineage.;
Uberon synonym : cephalic neural crest; head NCC population; CNC; cranial NCC population;
Uberon related term : head neural crest; head crest;
Uberon Homology note : We conclude this section by listing some of the many synapomorphies of craniates,
including (1) the neural crest (...).[well established][VHOG];
Origin ID : 0003099;
Automatic exact mappings (from CISMeF team)
develops into
has part
part of
neural crest cells (NCCs) originating in the anterior part of the developing embryo
and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs
migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into
various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues
of the face; these cells enter the pharyngeal pouches and arches where they give rise
to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts
of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute
to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte)
lineage.