Preferred Label : adenohypophysis;
Uberon definition : The glandular, anterior lobe of the pituitary gland. The anterior pituitary regulates
several physiological processes including stress, growth, and reproduction[WP]. The
anterior lobe of the hypophysis (pituitary gland). This lobe contains cells that produce
prolactin, growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone
and proopiomelanocortin[ZFA].;
Uberon synonym : pituitary gland, anterior lobe; anterior pituitary; anterior hypophysis; anterior lobe of hypophysis; anterior lobe of pituitary; anterior lobe of pituitary gland; anterior lobe (hypophysis);
Uberon related term : rostral lobe; cranial lobe; anterior pituitary gland; pituitary anterior lobe; pituitary glandanterior lobe; anterior lobe of the pituitary;
Uberon broad term : AHP;
Uberon Homology note : It (the hypophysis) develops embryonically in all vertebrates from two ectodermal
evaginations that meet and unite. An infundibulum grows ventrally from the diencephalon
of the brain, and Rathke's pouch extends dorsally from the roof of the developing
mouth, or stomodaeum. The infundibulum remains connected to the floor of the diencephalon,
which becomes the hypothalamus, and gives rise to the part of the gland known as the
neurohypophysis. (...) Rathke's pouch loses its connection with the stomodaeum in
most adult vertebrates and gives rise to the rest of the gland, the adenohypophysis.
(...) A well-developed hypophyseal system with functional connections to the hypothalamus
is unique to craniates.[well established][VHOG];
Uberon Taxon note : While in most basal fish and tetrapods the adenohypophyseal anlagen invaginates to
form Rathke's pouch, in teleost fish the adenohypophyseal placode does not invaginate
but rather maintains its initial organization forming a solid structure in the head[NCBIBook:NBK53175].;
Origin ID : 0002196;
Automatic exact mappings (from CISMeF team)
Uberon cross reference
contributes to morphology of
develops from
has part
part of
The glandular, anterior lobe of the pituitary gland. The anterior pituitary regulates
several physiological processes including stress, growth, and reproduction[WP]. The
anterior lobe of the hypophysis (pituitary gland). This lobe contains cells that produce
prolactin, growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone
and proopiomelanocortin[ZFA].