Uberon definition : A monolayer of pigmented epithelium covering the neural retina; develops from the
outer of the two layers of the optic cup[ZFA]. the pigmented cell layer just outside
the neurosensory retina that nourishes retinal visual cells, and is firmly attached
to the underlying choroid and overlying retinal visual cells[WP].;
Uberon related term : retinal pigment layer; PRE; RPE; pigmented retina; pigmented epithelium; epithelium, retinal pigment;
Uberon Homology note : (...) an essentially similar sequence of events occurs during the embryonic development
of the vertebrate eye. The eye initially develops as a single median evagination of
the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic
vesicle grows towards the body surface, its proximal part narrows as the optic stalk,
and its distal part invaginates to form a two-layered optic cup. (...) The outer layer
of the optic cup becomes the pigment layer of the retina, whereas the inner layer
differentiates into the photoreceptive cells and neuronal layers of the retina.[well
established][VHOG];
A monolayer of pigmented epithelium covering the neural retina; develops from the
outer of the two layers of the optic cup[ZFA]. the pigmented cell layer just outside
the neurosensory retina that nourishes retinal visual cells, and is firmly attached
to the underlying choroid and overlying retinal visual cells[WP].