Preferred Label : presumptive retinal pigmented epithelium;
Uberon definition : Portion of tissue that is the outer layer of the optic cup and will become the retinal
pigmented epithelium.;
Uberon synonym : outer layer optic cup; presumptive pigmented epithelia; future RPE; future retinal pigmented epithelium; optic cup outer layer;
Uberon related term : future pigmented layer; future pigmented retinal epithelium; presumptive pigmented epithelium; future PRE;
Uberon Homology note : (...) an essentially similar sequence of events occurs during the embryonic development
of the vertebrate eye. The eye initially develops as a single median evagination of
the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic
vesicle grows towards the body surface, its proximal part narrows as the optic stalk,
and its distal part invaginates to form a two-layered optic cup. (...) The outer layer
of the optic cup becomes the pigment layer of the retina, whereas the inner layer
differentiates into the photoreceptive cells and neuronal layers of the retina.[well
established][VHOG];
Origin ID : 0005424;
develops into
- has potential to develop into
- part of
Portion of tissue that is the outer layer of the optic cup and will become the retinal
pigmented epithelium.
