Preferred Label : dementia with Lewy bodies;
Definition : A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations
in attention and alertness. The neuropsychiatric manifestations tend to precede the
onset of bradykinesia, muscle rigidity, and other extrapyramidal signs. delusions
and visual hallucinations are relatively frequent in this condition. Histologic examination
reveals lewy bodies in the cerebral cortex and brain stem. senile plaques and other
pathologic features characteristic of alzheimer disease may also be present. (From
Neurology 1997;48:376-380; Neurology 1996;47:1113-1124) [MeSH];
UMLS CUI (RADLEX) : C0752347;
Origin ID : RID5142;
UMLS CUI : C0752347;
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations
in attention and alertness. The neuropsychiatric manifestations tend to precede the
onset of bradykinesia, muscle rigidity, and other extrapyramidal signs. delusions
and visual hallucinations are relatively frequent in this condition. Histologic examination
reveals lewy bodies in the cerebral cortex and brain stem. senile plaques and other
pathologic features characteristic of alzheimer disease may also be present. (From
Neurology 1997;48:376-380; Neurology 1996;47:1113-1124) [MeSH]