NCIt definition : A fusion protein (680 aa, 75 kDa) that is encoded by the CARS/ALK fusion gene. This
protein contains 606 amino acids from the N-terminus of the cysteinyl-tRNA synthetase,
cytoplasmic protein and the cytoplasmic domain of the ALK tyrosine kinase receptor
protein.;
NCIt note : The CARS/ALK fusion protein is a constitutively dimerized and activated tyrosine kinase.;