FGFR1OP2/FGFR1 Fusion Protein

Preferred Label : FGFR1OP2/FGFR1 Fusion Protein;

NCIt synonyms : FGFR1OP2-FGFR1 Fusion Protein; FGFR1 Oncogene Partner 2/Basic Fibroblast Growth Factor Receptor 1 Fusion Protein; FGFR1OP2::FGFR1 Fusion Protein;

NCIt definition : A fusion protein (526 aa, 60 kDa) encoded by the FGFR1OP2/FGFR1 fusion gene. This protein is comprised of the first 2 coiled-coil domains of the FGFR1 oncogene partner 2 protein followed by the tyrosine kinase domains of the basic fibroblast growth factor receptor 1.;

NCIt note : The FGFR1OP2/FGFR1 fusion protein is a constitutively dimerized and activated tyrosine kinase.;

Details

Origin ID

C99836;

UMLS CUI

C3274994;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FGFR1OP2/FGFR1 Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
related_to_genetic_biomarker
- FGFR1 Gene [NCIt concept]
- FGFR1OP2 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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