BRD4/NUTM1 Fusion Gene

Preferred Label : BRD4/NUTM1 Fusion Gene;

NCIt synonyms : BRD4-C15orf55 Fusion Gene; BRD4-NUT Fusion Gene; NUT/BRD4 Fusion Gene; BRD4/NUT Fusion Gene; BRD4-NUTM1 Fusion Gene; BRD4/C15orf55 Fusion Gene; BRD4::NUTM1 Fusion Gene;

NCIt definition : A fusion gene ( 6 kb) that results from a chromosomal translocation t(15;19)(q14;p13) which fuses the first 10 exons of the BRD4 gene with exon 2 of the NUTM1 gene. This rearrangement is associated with a rare, aggressive, and lethal carcinoma arising in midline organs of young people.;

GenBank Accession Number : AY166680;

Détails

Origin ID

C99831;

UMLS CUI

C3274991;

Automatic exact mappings (from CISMeF team)
- Bromodomain-containing protein 4 [OMIM gene]
- Nut midline carcinoma family member 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Pediatric Oncology Target Molecular Abnormalities Terminology [NCIt concept]
gene_encodes_gene_product
- BRD4/NUTM1 Fusion Protein [NCIt concept]
gene_has_abnormality
- t(15;19)(q13;p13.1) [NCIt concept]
gene_involved_in_molecular_abnormality
- BRD4-NUTM1 Fusion Protein Expression [NCIt concept]
- t(15;19)(q13;p13.1) [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- NUT Carcinoma [NCIt concept]
gene_mapped_to_disease
- Advanced NUT Carcinoma [NCIt concept]
- Childhood Head and Neck NUT Carcinoma [NCIt concept]
- Childhood NUT Carcinoma [NCIt concept]
- Head and Neck NUT Carcinoma [NCIt concept]
- Mediastinal/Thymus NUT Carcinoma [NCIt concept]
- Metastatic NUT Carcinoma [NCIt concept]
- NUT Carcinoma [NCIt concept]
- Primary Cutaneous NUT Adnexal Carcinoma [NCIt concept]
- Sinonasal NUT Carcinoma [NCIt concept]
- Thoracic NUT Carcinoma [NCIt concept]
- Unresectable NUT Carcinoma [NCIt concept]
genetic_biomarker_related_to
- BRD4/NUTM1 Fusion Negative [NCIt concept]
related_to_genetic_biomarker
- BRD4 Gene [NCIt concept]
- NUTM1 Gene [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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