Mediastinal/Thymus NUT Carcinoma

Preferred Label : Mediastinal/Thymus NUT Carcinoma;

NCIt synonyms : Mediastinal/Thymic NUT Carcinoma;

NCIt definition : A highly aggressive, poorly differentiated carcinoma that arises from the mediastinum/thymus. It is characterized by mutations and rearrangement of the NUT gene.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL544717;

Details

Origin ID

C146706;

UMLS CUI

C4687430;

Disease excludes abnormal cell
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Excludes anatomical site(s)
- Neck [NCIt concept]
Has associated anatomic sites
- Respiratory System [NCIt concept]
- Thoracic Cavity [NCIt concept]
- Thymus Gland [NCIt concept]
Has cytogenetic abnormalities
- t(15;19)(q13;p13.1) [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_cytogenetic_abnormality
- Loss of Chromosome 13q [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
disease_has_finding
- Aggressive Clinical Course [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Poorly Differentiated Lesion [NCIt concept]
disease_has_molecular_abnormality
- BRD4-NUTM1 Fusion Protein Expression [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Thymic Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thymic Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Midline Anatomic Structure [NCIt concept]
- Thoracic Cavity [NCIt concept]
- Thymus Gland [NCIt concept]
disease_mapped_to_gene
- BRD4/NUTM1 Fusion Gene [NCIt concept]

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