FIP1L1/PDGFRA Fusion Gene

Preferred Label : FIP1L1/PDGFRA Fusion Gene;

NCIt synonyms : PDGFRA/FIP1L1 Fusion Gene; FIP1L1-PDGFRA Fusion Gene; FIP1L1::PDGFRA Fusion Gene;

NCIt definition : A fusion gene ( 2.6 kb) that results from a chromosomal deletion del(4)(q12q12) which fuses the 5' half of the FIP1L1 gene to the 3' part of the PDGFRA gene. This rearrangement is associated with myeloproliferative disorders.;

GenBank Accession Number : AY229892;

Details

Origin ID

C99743;

UMLS CUI

C1868219;

Automatic exact mappings (from CISMeF team)
- Fip1-like 1 [OMIM gene]
- Platelet-derived growth factor receptor, alpha [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FIP1L1/PDGFRA Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- FIP1L1-PDGFRalpha Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Myeloid/Lymphoid Neoplasms with PDGFRA Rearrangement [NCIt concept]
gene_mapped_to_disease
- Chronic Eosinophilic Leukemia with FIP1L1-PDGFRA [NCIt concept]
- Myeloid/Lymphoid Neoplasms with PDGFRA Rearrangement [NCIt concept]
gene_plays_role_in_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- FIP1L1 Gene [NCIt concept]
- PDGFRA Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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