Myeloid/Lymphoid Neoplasms with PDGFRA Rearrangement

Preferred Label : Myeloid/Lymphoid Neoplasms with PDGFRA Rearrangement;

NCIt synonyms : Myeloid and Lymphoid Neoplasms with PDGFRA Rearrangement; M/LN-eo with PDGFRA Rearrangement; Myeloid/Lymphoid Neoplasm with PDGFRA Rearrangement;

NCIt definition : Hematologic neoplasms characterized by the rearrangement of the PDGFRA gene, most often resulting in the formation of FIP1L1-PDGFRA fusion transcripts. Patients usually present with chronic eosinophilic leukemia, and less often with acute myeloid leukemia or T-lymphoblastic leukemia.;

Neoplastic status : Malignant;

ICD-O code : 9965/3;

Details

Origin ID

C84275;

UMLS CUI

C2827360;

Automatic exact mappings (from CISMeF team)
- Myeloid and lymphoid neoplasms with PDGFRA rearrangement [ICD-11 Extension code]
- Myeloid-lymphoid neoplasm with PDGFRA rearrangement (morphologic abnormality) [SNOMED CT concept]
- myeloid and lymphoid neoplasms associated with PDGFRA rearrangement [DO Concept]
DO Cross reference
- myeloid and lymphoid neoplasms associated with PDGFRA rearrangement [DO Concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Myeloid-lymphoid neoplasm with PDGFRA rearrangement (morphologic abnormality) [SNOMED CT concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_excludes_molecular_abnormality
- BCR-ABL1 Fusion Protein Expression [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_molecular_abnormality
- PDGFRA Gene Rearrangement [NCIt concept]
- Tyrosine Kinase Gene Fusion [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Pluripotent Stem Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
disease_mapped_to_gene
- FIP1L1/PDGFRA Fusion Gene [NCIt concept]
- PDGFRA Gene [NCIt concept]
disease_may_have_molecular_abnormality
- FIP1L1-PDGFRalpha Fusion Protein Expression [NCIt concept]
pathogenesis_of_disease_involves_gene
- FIP1L1/PDGFRA Fusion Gene [NCIt concept]
- PDGFRA Gene [NCIt concept]
- PDGFRA wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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