Transcription Factor Spi-B

Preferred Label : Transcription Factor Spi-B;

NCIt definition : Transcription factor Spi-B (262 aa, 29 kDa) is encoded by the human SPIB gene. This protein is involved in transcriptional activation.;

NCIt note : Transcription factor Spi-B binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. (UniProt);

Details

Origin ID

C99653;

UMLS CUI

C3274852;

Automatic exact mappings (from CISMeF team)
- Spi-B transcription factor [ORDO Gene]
- Spi-B transcription factor [HGNC gene]
- Spib transcription factor [OMIM gene]
OMIM relation
- Spib transcription factor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- SPIB Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- B-Lymphocyte [NCIt concept]
- Plasmacytoid Dendritic Cell [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- ETS Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- ETS Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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