" /> RARA/ZBTB16 Fusion Protein - CISMeF





Preferred Label : RARA/ZBTB16 Fusion Protein;

NCIt synonyms : RARA-ZBTB16 Fusion Protein; RARA/PLZF Fusion Protein; RARA-PLZF Fusion Protein; Retinoic Acid Receptor Alpha/Zinc Finger and BTB Domain-Containing Protein 16 Fusion Protein; RARA::ZBTB16 Fusion Protein;

NCIt definition : A fusion protein encoded by the RARA/ZBTB16 fusion gene. This protein is comprised of the N-terminal transcriptional activation domain of the retinoic acid receptor alpha protein fused to the seven C-terminal zinc fingers of zinc finger and BTB domain-containing protein 16.;

NCIt note : Due the alternative splicing of the RARA gene, two forms of the RARA/ZBTB16 fusion protein can be detected: RARA/ZBTB16 Isoform A1 (277 amino acids; 31 kDa) or RARA/ZBTB16 Isoform A2 (274 amino acids; 31 kDa) is comprised of either the A1 or A2 transcriptional activation domain of the retinoic acid receptor alpha protein, respectively. (Atlas of Genetics and Cytogenetics in Oncology and Haematology);

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30/05/2025


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