RARA/ZBTB16 Fusion Gene

Preferred Label : RARA/ZBTB16 Fusion Gene;

NCIt synonyms : RARA/PLZF Fusion Gene; RARA-ZBTB16 Fusion Gene; RARA-PLZF Fusion Gene; RARA::ZBTB16 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(11;17)(q23;q21) which fuses the exon 3 of the RARA gene to the 3' portion of the ZBTB16 gene. This rearrangement is associated with acute promyelocytic leukemia.;

Details

Origin ID

C99372;

UMLS CUI

C2674270;

Automatic exact mappings (from CISMeF team)
- Retinoic acid receptor, alpha [OMIM gene]
- Zinc finger- and btb domain-containing protein 16 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- RARA/ZBTB16 Fusion Protein [NCIt concept]
gene_has_abnormality
- t(11;17)(q23;q21) [NCIt concept]
gene_involved_in_molecular_abnormality
- t(11;17)(q23;q21) [NCIt concept]
related_to_genetic_biomarker
- RARA Gene [NCIt concept]
- ZBTB16 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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