MLL/FNBP1 Fusion Protein

Preferred Label : MLL/FNBP1 Fusion Protein;

NCIt synonyms : MLL-FNBP1 Fusion Protein; MLL/FBP17 Fusion Protein; MLL-FBP17 Fusion Protein; Histone-Lysine N-Methyltransferase MLL/Formin-Binding Protein 1 Fusion Protein; MLL::FNBP1 Fusion Protein; KMT2A::FNBP1 Fusion Protein;

NCIt definition : A fusion protein encoded by the MLL/FNBP1 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to almost the entire formin-binding protein 1.;

NCIt note : This fusion protein is localized to the nucleus; in contrast, the formin-binding protein 1 is localized to lysosomes and endosomes. (Atlas of Genetics and Cytogenetics in Oncology and Haematology);

Details

Origin ID

C99328;

UMLS CUI

C3274684;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- MLL/FNBP1 Fusion Gene [NCIt concept]
related_to_genetic_biomarker
- FNBP1 Gene [NCIt concept]
- KMT2A Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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