Transcription Factor 12

Preferred Label : Transcription Factor 12;

NCIt synonyms : TCF12; E-Box-Binding Protein; TCF-12; DNA-Binding Protein HTF4; bHLHb20; Class B Basic Helix-Loop-Helix Protein 20; Transcription Factor HTF-4;

NCIt definition : Transcription factor 12 (682aa, 73 kDa) is encoded by the human TCF12 gene. This protein is involved in transcriptional regulation that modulates tissue differentiation.;

NCIt note : Transcription factor 12 activates transcription by binding to the E box (5'-CANNTG-3'). (UniProt);

Details

Origin ID

C97830;

UMLS CUI

C1435543;

OMIM relation
- Transcription factor 12 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TCF12 protein, human [MeSH Supplementary Concept]
- TCF12 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TCF12 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Immune Response Process [NCIt concept]
- Myogenesis [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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