Suppressor of Fused Homolog

Preferred Label : Suppressor of Fused Homolog;

NCIt synonyms : SUFU; SUFUH;

NCIt definition : Suppressor of fused homolog (484 aa, 54 kDa) is encoded by the human SUFU gene. This protein plays a role in both the hedgehog pathway and transcriptional modulation.;

Details

Origin ID

C97821;

UMLS CUI

C3273645;

OMIM relation
- Sufu negative regulator of hedgehog signaling [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- SUFU Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_is_element_in_pathway
- Basal Cell Carcinoma Pathway [NCIt concept]
- Hedgehog Signaling Events Mediated by Gli Family Proteins [NCIt concept]
- Hedgehog Signaling Pathway [NCIt concept]
- Sonic Hedgehog Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Signal Transduction [NCIt concept]
- Skeletal Development [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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