SRSF3 wt Allele

Preferred Label : SRSF3 wt Allele;

NCIt synonyms : SRp20; Serine/Arginine-Rich Splicing Factor 3 wt Allele; SFRS3;

NCIt definition : Human SRSF3 wild-type allele is located in the vicinity of 6p21 and is approximately 10 kb in length. This allele, which encodes serine/arginine-rich splicing factor 3 protein, is involved in both the splicing and transport of mRNA.;

NCIt note : A chromosomal translocation t(3;6)(q27;p21) involving the SRSF3 gene and the BCL6 gene may be associated with follicular lymphoma. There are few studies of this rearrangement so its epidemiology is still in question. (Atlas of Genetics and Cytogenetics in Oncology and Haematology);

GenBank Accession Number : L10838;

Details

Origin ID

C97786;

UMLS CUI

C3273626;

OMIM relation
- Splicing factor, serine/arginine-rich, 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21 [NCIt concept]
gene_is_element_in_pathway
- Spliceosome Pathway [NCIt concept]
gene_plays_role_in_process
- Intracellular Transport [NCIt concept]
- Ligand Binding [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Splicing [NCIt concept]
- Transcription Termination [NCIt concept]
- Transport Process [NCIt concept]
- mRNA Export [NCIt concept]

Keyword's position in hierarchy(ies) :

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