Endothelial Transcription Factor GATA-2

Preferred Label : Endothelial Transcription Factor GATA-2;

NCIt synonyms : GATA2; GATA-Binding Protein 2;

NCIt definition : Endothelial transcription factor GATA-2 (480 aa, 51 kDa) is encoded by the human GATA2 gene. This protein is involved in both sequence-specific DNA binding and the modulation of transcription.;

NCIt note : Endothelial transcription factor GATA-2 binds to the consensus sequence 5'-AGATAG-3'. (UniProt);

Details

Origin ID

C97554;

UMLS CUI

C1506956;

Automatic exact mappings (from CISMeF team)
- GATA binding protein 2 [ORDO Gene]
- Gata-binding protein 2 [OMIM gene]
- gata2 transcription factor [MeSH Descriptor]
OMIM relation
- Gata-binding protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GATA2 protein, human [MeSH concept]
- GATA2 protein, human [MeSH Supplementary Concept]
- GATA2 transcription factor [MeSH concept]
- gata2 transcription factor [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GATA2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Gata-Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Androgen Receptor Regulation Pathway [NCIt concept]
- HDAC Class I Signaling Pathway [NCIt concept]
- HDAC Class II Signaling Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Phagocytosis [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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