CLP1 wt Allele

Preferred Label : CLP1 wt Allele;

NCIt synonyms : hClp1; ATP/GTP-Binding Protein Gene; CLP1, Cleavage and Polyadenylation Factor I Subunit, Homolog (S. cerevisiae) Gene; HEAB; Cleavage Factor Polyadenylation Kinase Subunit 1 wt Allele;

NCIt definition : Human CLP1 wild-type allele is located in the vicinity of 11q12 and is approximately 13 kb in length. This allele, which encodes polyribonucleotide 5'-hydroxyl-kinase Clp1 protein, is involved in the mediation of RNA maturation.;

NCIt note : A complex chromosomal aberration invins(10;11)(p12;q23q12) is associated with acute monoblastic leukemia. This rearrangement fuses the MLL gene with the MLLT10 gene and the 5' portion of the MLLT10 gene with the CPL1 gene. The MLLT10/CLP1 fusion transcript is out of frame. (OMIM);

GenBank Accession Number : BC000446;

Details

Origin ID

C97529;

UMLS CUI

C3273471;

OMIM relation
- Cleavage factor polynucleotide kinase subunit 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q12 [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- RNA Splicing [NCIt concept]

Keyword's position in hierarchy(ies) :

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