EIF4A2 wt Allele

Preferred Label : EIF4A2 wt Allele;

NCIt synonyms : EIF4A; eIF4A-II; BM-010; eIF-4A-II; DDX2B; EIF4F; Eukaryotic Translation Initiation Factor 4A2 wt Allele; Eukaryotic Translation Initiation Factor 4A, Isoform 2 Gene;

NCIt definition : Human EIF4A2 wild-type allele is located in the vicinity of 3q28 and is approximately 7 kb in length. This allele, which encodes eukaryotic initiation factor 4A-II, plays a role in the positive regulation of translation. A chromosomal translocation t(3;18)(q27;p11.2) of this gene and the BCL6 gene is associated with non-Hodgkin lymphoma.;

GenBank Accession Number : D30655;

Details

Origin ID

C97468;

UMLS CUI

C3273427;

Automatic exact mappings (from CISMeF team)
- Eukaryotic translation initiation factor 4E [ORDO Gene]
- Eukaryotic translation initiation factor 4a, isoform 2 [OMIM gene]
- eukaryotic initiation Factor-4A [MeSH Descriptor]
- eukaryotic initiation Factor-4F [MeSH Descriptor]
- eukaryotic translation initiation factor 4 gamma 1 [ORDO Gene]
- eukaryotic translation initiation factor 4F complex [GO term]
OMIM relation
- Eukaryotic translation initiation factor 4a, isoform 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3q28 [NCIt concept]
gene_is_element_in_pathway
- Protein Translation Pathway [NCIt concept]
- eIF4 Regulation Pathway [NCIt concept]
gene_plays_role_in_process
- ATP Hydrolysis [NCIt concept]
- Hydrolysis [NCIt concept]
- RNA Polyadenylation Regulation [NCIt concept]
- Translation Initiation [NCIt concept]
- Translation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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