Unmutated Immunoglobulin Heavy Chain Variable Region Gene

Preferred Label : Unmutated Immunoglobulin Heavy Chain Variable Region Gene;

NCIt synonyms : IGHV Mutation Negative; Unmutated IGHV; IGHV Wildtype;

NCIt definition : A molecular finding indicating that the immunoglobulin heavy chain variable region has an unmutated germline configuration.;

NCIt note : The presence of unmutated germ line configuration of immunoglobulin heavy chain variable region genes is associated with a poor prognosis in cases of chronic lymphocytic leukemia.;

Details

Origin ID

C97146;

UMLS CUI

C3273255;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
is_molecular_abnormality_of_disease
- Chronic Lymphocytic Leukemia with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene [NCIt concept]
- Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene [NCIt concept]
- Small Lymphocytic Lymphoma with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene [NCIt concept]
molecular_abnormality_involves_gene
- Immunoglobulin Heavy Locus [NCIt concept]

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