Nimustine Hydrochloride

Preferred Label : Nimustine Hydrochloride;

NCIt synonyms : CS 439 HCl; 3-((4-Amino-2-Methyl-5-Pyrimidinyl)Methyl)-1-(2-Chloroethyl)-1-Nitrosourea Hydrochloride; N'-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea Hydrochloride; ACNU HCl;

NCIt definition : The hydrochloride salt of nimustine, a nitrosourea with antineoplastic activity. Nimustine alkylates and crosslinks DNA, thereby causing DNA fragmentation, inhibition of protein synthesis, and cell death.;

UNII : DFR965WKBU;

InChIKey : KPMKNHGAPDCYLP-UHFFFAOYSA-N;

CAS number : 42471-28-3;

Drug name : Nidran HCl;

Chemical formula : C9H13ClN6O2.ClH;

NSC code : 245382;

ChEBI ID : CHEBI:7576;

Codes from synonyms : NSC0245382;

Details

Origin ID

C95325;

UMLS CUI

C0771987;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- nimustine [MeSH Descriptor]
- nimustine [MeSH concept]
- nimustine [Substance BNPC]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Nimustine [NCIt concept]
is_salt_form_of
- Nimustine [NCIt concept]

Keyword's position in hierarchy(ies) :

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