nimustine - CISMeF

Preferred Label : nimustine;

MeSH definition : Antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine. The drug has also been used in combination with other antineoplastic agents or with radiotherapy for the treatment of various neoplasms.;

MeSH synonym : ACNU;

CISMeF synonym : 245382, NSC;

MeSH hyponym : NSC 245382;

MeSH CAS label : urea, N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitroso-;

MeSH Related Number : 42471-28-3 (Nimustine);

Registry Number MeSH : 42471-28-3;

Wikipedia link : https://en.wikipedia.org/wiki/Nimustine;

Codes EINECS : 255-838-1;

Is substance : O;

UNII : 0S726V972K;

InChIKey : VFEDRRNHLBGPNN-UHFFFAOYSA-N;

Details

Origin ID

D015376;

UMLS CUI

C0028096;

ATC code(s)
- nimustine [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Nimustine [ICHI extension code]
CISMeF manual mappings
- nimustine [Substance BNPC]
Currated CISMeF NLP mapping
- Nimustine [ICD-11 Extension code]
- Nimustine [NCIt concept]
Pharmacological action(s)
- antineoplastic agents [MeSH Descriptor]
Record concept(s)
- NSC 245382 [MeSH concept]
- nimustine [MeSH concept]
Related MeSH Supplementary Concept(s)
- AAABC protocol [MeSH Supplementary Concept]
- AAAP protocol [MeSH Supplementary Concept]
- AVN protocol [MeSH Supplementary Concept]
- CE-AVN protocol [MeSH Supplementary Concept]
- COMP-VAN protocol [MeSH Supplementary Concept]
- DAV protocol [MeSH Supplementary Concept]
- PAV protocol [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Nimustine [ICD-11 Extension code]
- Nimustine [NCIt concept]
- nimustine [ATC Code]
- nimustine [Substance BNPC]
Validated automatic mappings to BTNT
- Nimustine Hydrochloride [NCIt concept]
- nimustine [ATC Code]

Keyword's position in hierarchy(ies) :

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