NCIt synonyms : RPRGL1; PCCF; Coagulation Factor V wt Allele; Coagulation Factor V (Proaccelerin, Labile Factor) Gene; THPH2;
NCIt definition : Human F5 wild-type allele is located in the vicinity of 1q23 and is approximately
75 kb in length. This allele, which encodes coagulation factor V protein, is involved
in the mediation of coagulation. Mutation of the gene is associated with hemorrhagic
diathesis in factor V deficiency, Budd-Chiari syndrome, thrombophilia due to activated
protein C resistance and susceptibility to ischemic stroke.;