NCIt definition : An orally available mesylate salt form of the etexilate prodrug of dabigatran, a benzimidazole
and direct thrombin inhibitor with anticoagulant activity. Upon administration, dabigatran
etexilate is hydrolyzed by esterases and is converted into dabigatran. Dabigatran
reversibly binds to and inhibits the activity of thrombin, a serine protease that
converts fibrinogen into fibrin. This disrupts the coagulation cascade and inhibits
the formation of blood clots.;