Preferred Label : Dabigatran Etexilate Mesylate;

NCIt synonyms : Beta-alanine, N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl] phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-,ethyl ester, methanesulfonate;

NCIt definition : An orally available mesylate salt form of the etexilate prodrug of dabigatran, a benzimidazole and direct thrombin inhibitor with anticoagulant activity. Upon administration, dabigatran etexilate is hydrolyzed by esterases and is converted into dabigatran. Dabigatran reversibly binds to and inhibits the activity of thrombin, a serine protease that converts fibrinogen into fibrin. This disrupts the coagulation cascade and inhibits the formation of blood clots.;

UNII : SC7NUW5IIT;

InChIKey : XETBXHPXHHOLOE-UHFFFAOYSA-N;

CAS number : 593282-20-3; 872728-81-9;

Drug name : Pradaxa;

Molecule name : BIBR 1048 MS; BIBR 1048MS;

Chemical formula : C34H41N7O5.CH4O3S;

Details


Main resources

You can consult :


https://www.has-sante.fr/jcms/p_3478094/fr/pradaxa-dabigatran-etexilate-traitement-des-evenements-thromboemboliques-veineux-etev-pediatrique
2024
false
false
false
France
child
adolescent
evaluation of the transparency committee
pediatrics
During Treatment
Biomaterial Treatment
Treatment
Venous Thromboembolism
Dabigatran Etexilate Mesylate
Treatment Study
pediatrician
On Treatment
venous thromboembolism
GDC Treatment Frequency Terminology
Treatment Epoch
Pediatric
vein, nos
Childhood-Onset Systemic Lupus Erythematosus
Thromboembolic Event, CTCAE
Pradaxa
Pediatric
Pediatricians
Therapy Object
Dabigatran Etexilate
dabigatran etexilate
thromboembolus
No Treatment for Diabetes
Dabigatran
thromboembolism
Treat

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10/05/2025


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