Acute Myelomonocytic Leukemia with Abnormal Eosinophils

Preferred Label : Acute Myelomonocytic Leukemia with Abnormal Eosinophils;

NCIt synonyms : FAB M4Eo; AMML Eo; M4eo; M4 eos; M4eos; M4 eo;

NCIt definition : Acute myelomonocytic leukemia characterized by the presence of abnormal bone marrow eosinophils. It is associated with inv(16)(p13.1;q22) or t(16;16)(p13.1;q22). It has a favorable prognosis.;

Neoplastic status : Malignant;

Details

Origin ID

C9020;

UMLS CUI

C1332156;

Automatic exact mappings (from CISMeF team)
- Acute myeloid leukaemia with abnormal marrow eosinophils [ICD-11 Extension code]
- Acute myeloid leukemia with CBFB::MYH11 fusion (morphologic abnormality) [SNOMED CT concept]
- acute myelomonocytic leukemia with eosinophils [SNOMED Notion]
Disease excludes abnormal cell
- Neoplastic Lymphoblast [NCIt concept]
Disease excludes normal cell origin
- Lymphocyte [NCIt concept]
Disease may have findings
- Auer Rods Present [NCIt concept]
- Fatigue [NCIt concept]
- Favorable Clinical Outcome [NCIt concept]
- Fever [NCIt concept]
- Hypercellular Bone Marrow [NCIt concept]
- Leukocytosis [NCIt concept]
- Thrombocytopenia [NCIt concept]
Has associated anatomic sites
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- acute myelomonocytic leukemia with eosinophils [SNOMED Notion]
associated_with_malfunction_of_gene_product
- Core-Binding Factor Subunit Beta [NCIt concept]
concept_is_in_subset
- AML Authorized Value Terminology [NCIt concept]
- AML Disease Characteristics Table [NCIt concept]
- CPTAC Acute Myeloid Leukemia Baseline Form [NCIt concept]
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Bone Marrow Dysplasia Present in 50 Percent or More of the Cells of Two Cell Lines [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Abnormal Eosinophil [NCIt concept]
- Leukemic Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Monoblast [NCIt concept]
- Neoplastic Monocyte [NCIt concept]
- Neoplastic Myeloblast [NCIt concept]
- Neoplastic Myeloid Cell [NCIt concept]
- Neoplastic Neutrophilic Precursor [NCIt concept]
- Neoplastic Promonocyte [NCIt concept]
disease_has_finding
- Abnormal Eosinophilic Granules Present [NCIt concept]
- Blasts 20 Percent or More of Bone Marrow Nucleated Cells [NCIt concept]
- Blasts 20 Percent or More of Peripheral Blood White Cells [NCIt concept]
- Bone Marrow Eosinophilia [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neoplastic Granulocytes and Precursors 20 Percent or More of Bone Marrow Cells [NCIt concept]
- Neoplastic Monocytes and Precursors 20 Percent or More of Bone Marrow Cells [NCIt concept]
- Not Otherwise Specified Lesion [NCIt concept]
disease_has_normal_cell_origin
- Bone Marrow Stem Cell [NCIt concept]
- Granulocyte-Monocyte Progenitor Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic Tissue [NCIt concept]
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_mapped_to_gene
- CBFB Gene [NCIt concept]
- MYH11 Gene [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
pathogenesis_of_disease_involves_gene
- CBFB Gene [NCIt concept]
- CBFB wt Allele [NCIt concept]
- MYH11 Gene [NCIt concept]
- MYH11 wt Allele [NCIt concept]

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